Bimekizumab in Plaque Psoriasis

Part of paid clinical trials in East Windsor, New Jersey.

Sponsor
Icahn School of Medicine at Mount Sinai
Study ID
NCT06336343
Phase
PHASE4
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Bimekizumab — DRUG
    Bimekizumab 320 mg via subcutaneous injections. Bimekizumab is a humanized immunoglobulin G1 monoclonal antibody that selectively binds to and neutralizes the biologic functions of both interleukin-17A (IL-17A) and IL-17F, which are known to increase inflammation.

Study Details

The purpose of this research study is to evaluate the effectiveness and safety of bimekizumab in individuals with moderate-to-severe psoriasis who have failed similar therapies. Bimekizumab improves psoriasis by suppressing a type of substance found in bodies called interleukins (specifically, interleukins 17a and 17F), which are known to increase inflammation. This study will look at the effectiveness of bimekizumab in psoriasis patients that have failed previous therapies that target interleukin IL-17A or 23.

Key Dates

Start date
Jun 3, 2024
Status verified
Apr 2026
Primary completion
Mar 17, 2026
Completion
Mar 17, 2026

Study Design

Enrollment
60 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Individuals with moderate-to-severe psoriasis
    Individuals with moderate-to-severe psoriasis who have failed similar therapies.

Primary Outcome Measure

Body Surface Area (BSA) of < 1 [ Time Frame: Baseline, Week 4, Week 8, Week 12, Week 16 ]

Locations (2)

FacilityCityStateZIPSite coordinators
Windsor Dermatology - Psoriasis Treatment Center of Central New JerseyEast WindsorNew Jersey08520-
Icahn School of Medicine at Mount SinaiNew YorkNew York10029-

Find similar trials in East Windsor, NJ

By condition
Psoriasis
By specialty
DermatologyRheumatologyAutoimmune disease
By research site
Windsor Dermatology - Psoriasis Treatment Center of Central New Jersey· East Windsor, NJIcahn School of Medicine at Mount Sinai· New York, NY

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