Brain Mechanisms of Reducing Polysubstance Use

Conditions

• Multiple Drug Use

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Accepted

Interventions

• IBMT — BEHAVIORAL
  IBMT is an effortless mindfulness technique
• NF — BEHAVIORAL
  NF is a mental training technique.

Study Details

The proposed study will test whether neurofeedback (NF) could optimize integrative body-mind training (IBMT) practice.

Key Dates

Start date

Sep 1, 2023

Status verified

May 2026

Primary completion

Aug 31, 2027

Completion

Aug 31, 2027

Study Design

Enrollment

35 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Arms

• Experimental: IBMT
  An evidence-based preventive intervention - integrative body-mind training (IBMT) has shown positive effects in reducing stress and improving self-control and brain plasticity. It has bodifulness and mindfulness components.
• Experimental: NF
  An evidence-based intervention - NF can not only provide real-time feedback for practice but also target the self-control networks, suggesting the possibility of augmenting IBMT effects via NF.
• Experimental: IBMT + NF
  The combined IBMT and NF also show positive effects in reducing substance use.
• Sham Comparator: Sham NF
  Sham NF has the same settings as the active NF but does not have correct parameters of stimulation.

Primary Outcome Measure

Intervention effects on brain function using Functional Magnetic Resonance Imaging (fMRI) [ Time Frame: The outcome measures are assessed in-person at baseline, 2-4 weeks and 3 months ]

Central Contacts

• YiYuan Tang
  4807903577
  [email protected]

Locations (1)

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