Enhancing Prospective Thinking in Early Recovery (BEAM)

Part of paid clinical trials in Indianapolis, Indiana.

Sponsor
Indiana University
Study ID
NCT06283472
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Not accepted

Interventions

  • High-Intensity Cue — BEHAVIORAL
    Participants in the high-intensity group will receive high-intensity image cues that represent self-reported events they did on the previous day and self-reported events they look forward to in the future.
  • Low-Intensity Cue — BEHAVIORAL
    Participants in the low-intensity group will receive low-intensity image cues that represent self-reported events they did on the previous day and self-reported events they look forward to in the future.

Study Details

The goal of this clinical trial is to test the prosocial effects of personally-relevant, high-intensity episodic future-thinking (EFT) cues in alcohol use disorder persons and related brain mechanisms. The main question\[s\] this trial aims to answer are: * Will high-intensity EFT cues will produce greater delayed reward preference than low-intensity cues? * Will high-intensity EFT cues effect greater treatment-seeking interest? * Will high-intensity EFT cues elicit greater response in regions for prospective thinking during delay discounting (vs. low-intensity) * Will nucleus accumbens-precuneus resting connectivity correlate with behavioral SS? * Will the novel behavioral SS decision-making task activate the nucleus accumbens? Researchers will compare the experimental (high-intensity group) and control (low-intensity) groups to see if there are differences in the results for the questions outlined above.

Key Dates

Start date
Jun 17, 2024
Status verified
Dec 2025
Primary completion
Nov 30, 2027
Completion
Nov 30, 2027

Study Design

Enrollment
21 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE

Arms

  • Experimental: High-Intensity
    Participants will receive high-intensity episodic future-thinking cue images, and high-intensity episodic recent-thinking cue images during an MRI decision-making task.
  • Active Comparator: Low-Intensity (Control)
    Participants will receive low-intensity episodic future-thinking cue images, and low-intensity episodic recent-thinking cue images during an MRI decision-making task.

Primary Outcome Measure

Increase Prospective Thinking [ Time Frame: Study Day Visit (Day 1) ]

Locations (1)

FacilityCityStateZIPSite coordinators
Indiana University School of Medicine - Goodman HallIndianapolisIndiana46202
Sarah Turo, BA
[email protected]
317-963-7220
Brandon G Oberlin, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Indianapolis, IN

By condition
Substance use disorder
By specialty
Behavioral healthAddiction medicine
By research site
Indiana University School of Medicine - Goodman Hall· Indianapolis, IN

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