Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART)
Part of paid clinical trials in Falls Church, Virginia.
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
- Study ID
- NCT06280820
- Status
- Enrolling By Invitation
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 100 Years
- Healthy Volunteers
- Not accepted
Study Details
Background: More than 6.5 million people in the United States live with heart failure (HF), and more than a million new cases are diagnosed each year. Treatments have improved in recent years, but researchers want to understand more about how HF develops. To do this, they need to compare blood and other samples from many people with HF. Objective: To collect blood and other samples from people with HF. These samples will be used to identify and study proteins and other factors that may lead to decreased heart function over time. Eligibility: People aged 18 years and older with heart failure. Design: Participants will be asked to join the study based on a review of their medical records. They will have 1 study visit. They will provide a blood sample: About 3 tablespoons will be collected from a needle inserted into a vein. Other tests are optional: Participants may provide urine and stool samples. They may have a cotton swab rubbed on the inside of the mouth to collect DNA. Participants may also take 3 questionnaires. They will answer questions about dietary, social, and other factors that affect their health. Participants will receive compensation. Researchers will follow the participants health by monitoring their medical records for up to 5 years.
Key Dates
- Start date
- Jun 16, 2026
- Status verified
- Dec 2025
- Primary completion
- Apr 30, 2028
- Completion
- Apr 30, 2034
Study Design
- Enrollment
- 2,000 participants (estimated)
Arms
- Arm: Participants with heart conditionHeart Failure
Primary Outcome Measure
To study the association between multi-omics signatures with all-cause mortality [ Time Frame: 10 years ]
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| INOVA Fairfax Hospital | Falls Church | Virginia | 22042 | - |
Find similar trials in Falls Church, VA
Related Studies
- Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy ProductsRecruiting · Medtronic · Birmingham, Alabama
- The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMRRecruiting · Cardiac Dimensions, Inc. · Gilbert, Arizona
- Global Utilization And Registry Database for Improved heArt preservatioNEnrolling By Invitation · Paragonix Technologies · Stanford, California
- Hemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock TrialRecruiting · Inova Health Care Services · Falls Church, Virginia