Gut Microbiome Studies in Patients With POEMS Syndrome and Other Plasma Cell Disorders

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT06252948
Status
Recruiting
Apply to this trial

Conditions

  • Plasma Cell Disorders

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Non-interventional study (observational) — OTHER
    Participants undergo stool sample collection, complete surveys, and have their medical record reviewed on study.

Study Details

A Study to Evaluate Gut Microbiome with POEMS Syndrome and Other Plasma Cell Disorders

Key Dates

Start date
Dec 29, 2021
Status verified
Feb 2026
Primary completion
Dec 1, 2028
Completion
Dec 29, 2028

Study Design

Enrollment
240 participants (estimated)

Arms

  • Arm: MULTIPLE MYELOMA at diagnosis GROUP
    Multiple myeloma (before starting chemotherapy, radiation or stem cell transplant
  • Arm: Amyloid at diagnosis GROUP
    AL amyloidosis (before starting chemotherapy or stem cell transplant)
  • Arm: Poems at diagnosis GROUP
    POEMS at diagnosis (before starting chemotherapy, radiation, or stem cell transplant
  • Arm: Poems in Remission GROUP
    POEMS in remission (no chemotherapy, radiation, or stem cell transplant for 2 years
  • Arm: MGUS GROUP
    MGUS -not treated newly diagnosed
  • Arm: Health controls in same household GROUP
    household member to be a healthy control (no chemotherapy or gastrointestinal illness to participate)

Primary Outcome Measure

Gut Microbiome characteristics in patients with POEMS syndrome and other plasma cell disorders [ Time Frame: Baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic in RochesterRochesterMinnesota55905
Laura Hawkins
[email protected]
507-538-1308
Sarah Aug
[email protected]
507-538-1301
Angela Dispenzieri, M.D. (PRINCIPAL_INVESTIGATOR)

Find similar trials in Rochester, MN

By research site
Mayo Clinic in Rochester· Rochester, MN

Related Studies