Young Adult Tobacco/Nicotine and Cannabis Co-use

Part of paid clinical trials in Charleston, South Carolina.

Sponsor
Medical University of South Carolina
Study ID
NCT06239350
Status
Recruiting
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Conditions

  • Nicotine Dependence
  • Tobacco Use Disorder

Eligibility Criteria

Sex
ALL
Age
18 Years - 25 Years
Healthy Volunteers
Accepted

Interventions

  • Counseling — BEHAVIORAL
    Research staff will provide skills-based counseling at remote weekly visits, starting at Day 0. Counseling sessions will be brief (\~5-10 minutes) and will focus on strategies for preparing for the quit attempt, dealing with triggers, refusal skills, and enhancing motivation.
  • Contingency management — BEHAVIORAL
    Contingency management (CM): CM will be provided to all study participants to promote abstinence from all nicotine products. Incentives for abstinence (based on submission of a negative cotinine sample) will be provided on an escalating schedule during treatment (Days 8-84).
  • Text-based support — BEHAVIORAL
    All participants will be provided with evidence-based nicotine cessation resources. For those who are vaping nicotine, participants will be provided information for This is Quitting (SMS text-based program). For those who are primarily smoking cigarettes, NCI's QuitSTART (mobile app, web content), as well SmokefreeTXT (SMS-text based program), will be recommended, potentially in addition to This is Quitting for those using multiple products. These resources provide real time monitoring of nicotine use, mood, triggers and lapses.

Study Details

The goal of this project is to better understand the relationship between tobacco/nicotine and cannabis using behavioral economics during a tobacco/nicotine quit attempt. All participants will receive tobacco/nicotine cessation treatment (smoking and/or vaping treatment) for 12 weeks. To qualify, participants must be between the ages of 18-25 and use tobacco products (smoke cigarettes and/or vape nicotine) and use cannabis (in any form). Participants do not need to be interested in quitting cannabis/marijuana to qualify. This study is being conducted by the Medical University of South Carolina. All procedures are conducted remotely and there is no in-person visits are needed.

Key Dates

Start date
May 13, 2024
Status verified
Jun 2025
Primary completion
Oct 1, 2027
Completion
Jan 3, 2028

Study Design

Enrollment
350 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Other: Nicotine treatment
    All participants recieve active nicotine treatment for 12 weeks.

Primary Outcome Measure

7-day point prevalence nicotine abstinence at the end of treatment (Week 12) [ Time Frame: Final 7 days of treatment (Weeks 11-12 of tobacco treatment) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Medical University of South Carolina - CharlestonCharlestonSouth Carolina29403
Elizabeth Chapman
[email protected]
864-898-2992

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By research site
Medical University of South Carolina - Charleston· Charleston, SC

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