Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis

Conditions

• Carpometacarpal (CMC) Osteoarthritis

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Triamcinolone Acetonide extended release suspension — DRUG
  Active steroid

Study Details

The goal of this study is to investigate if a timed release steroid injection may be beneficial in treating carpometacarpal (CMC) joint (thumb) osteoarthritis. The main questions to be answered are: 1. does the steroid injection substantially reduce pain in the thumb 2. does the steroid injection help to increase thumb function Participants will be asked to undergo a thumb CMC joint injection and to attend follow up visits to assess pain and thumb function.

Key Dates

Start date

Nov 21, 2023

Status verified

Jan 2024

Primary completion

Dec 31, 2025

Completion

Dec 31, 2025

Study Design

Enrollment

30 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Arms

• Experimental: Triamcinolone acetonide extended release suspension injection
  Active drug treatment
• Placebo Comparator: Saline Placebo Injection
  Placebo comparator

Primary Outcome Measure

Visual Analog Pain Score [ Time Frame: Day 1 of injection to six months post injection ]

Locations (1)

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