Safety and Efficacy of Mesenchymal Stem Cells Associated With Chronic Pancreatitis Pain

Part of paid clinical trials in Charleston, South Carolina.

Sponsor
Medical University of South Carolina
Study ID
NCT06205342
Phase
EARLY_PHASE1
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Mesenchymal Stem Cells — DRUG
    Autologous bone marrow derived MSCs
  • Other: Placebo — OTHER
    Control

Study Details

This protocol aims to test whether an infusion of allogeneic bone marrow-derived mesenchymal stromal cells (BM-MSCs) can reduce pain associated with chronic pancreatitis (CP) and explore potential mechanisms of MSC action.

Key Dates

Start date
Jul 17, 2024
Status verified
Apr 2026
Primary completion
Jun 1, 2027
Completion
Jun 1, 2028

Study Design

Enrollment
48 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Experimental Cohort
    MSC
  • Placebo Comparator: Validation Cohort
    Placebo

Primary Outcome Measure

Change in Izbicki pain score (M6 vs. Baseline) [ Time Frame: 6 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Medical University of South CarolinaCharlestonSouth Carolina29425
Hongjun Wang, Ph.D.
[email protected]
843-792-1800
Charlton Strange III, MD
[email protected]
(843) 792-3174
Hongjun Wang, Ph.D. (PRINCIPAL_INVESTIGATOR)
Charlton Strange III, MD (SUB_INVESTIGATOR)

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Medical University of South Carolina· Charleston, SC

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