Communication Bridge 3 Study

Part of paid clinical trials in Chicago, Illinois.

Sponsor
University of Chicago
Study ID
NCT06191198
Phase
PHASE2
Status
Recruiting
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Conditions

  • Primary Progressive Aphasia

Eligibility Criteria

Sex
ALL
Age
18 Years - 100 Years
Healthy Volunteers
Not accepted

Interventions

  • Communication Bridge™ — BEHAVIORAL
    Evidence-based speech language therapy treatment will be compared and contrasted in the two arms of the study.
  • Evidence-Based Impairment Focused — BEHAVIORAL
    Evidence-based speech language therapy treatment will be compared and contrasted in the two arms of the study.

Study Details

This study will use a randomized controlled trial design to evaluate the effect of two evidence-based treatments for adults with mild-moderate Primary Progressive Aphasia (PPA). The aim of the study is to help us better understand the effects of speech-language therapy on communication abilities in individuals with PPA.

Key Dates

Start date
Aug 23, 2024
Status verified
May 2026
Primary completion
Jul 15, 2028
Completion
Jul 15, 2028

Study Design

Enrollment
200 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Communication Bridge™
    Participants receive Communication Bridge™, a multi-component, participation-focused, dyadic intervention in which both the person with PPA and their co-enrolled communication partner are intervention recipients. Communication Bridge™ is modelled on the Living with Aphasia: Framework for Outcome Measurement (A-FROM) and the Care Pathway Model that was developed for persons living with primary progressive aphasia. Consistent with participation-focused intervention models personally salient training stimuli are incorporated into all therapy activities in the Experimental arm.
  • Active Comparator: Evidence-Based Impairment Focused
    The Control arm includes a non-dyadic intervention in which the person with PPA is the active intervention recipient and their communication partner is in a supporting role. In the Control arm, participants receive a speech-language intervention designed to address impairment and functional limitations, comprised of activities that address word retrieval and 'automatic' speech production using fixed, non-personalized, stimuli across participants.

Primary Outcome Measure

Change in Communication Participation Person Centered Goals [ Time Frame: 5 assessment time points through study completion (up to 18 months) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Chicago - American School BuildingChicagoIllinois60637
Matthew Bona, MPH
[email protected]

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University of Chicago - American School Building· Chicago, IL

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