ADAPT Study: Assessing Diet, Appetite and Physiology Throughout Weight Loss Study)

Part of paid clinical trials in Seattle, Washington.

Sponsor
University of Washington
Study ID
NCT06174389
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Accepted

Interventions

  • Behavioral Weight Loss Program — BEHAVIORAL
    Behavioral Weight Loss Program is a modified version of the Diabetes Prevention Program.

Study Details

Behavioral weight loss programs for obesity can result in weight loss and health benefits. However, behavioral weight loss often stops despite efforts to continue losing weight, this can be called an involuntarily weight loss plateau. This study investigates changes in metabolism and/or the brain that contribute to the occurrence of an involuntary weight loss plateau.

Key Dates

Start date
Oct 1, 2023
Status verified
May 2025
Primary completion
Jul 31, 2027
Completion
Jul 31, 2027

Study Design

Enrollment
90 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Behavioral Weight Loss
    Participants will undergo a behavioral weight loss program.

Primary Outcome Measure

Change in maximal respiratory capacity (oxygen consumption rate) in peripheral blood mononuclear cells [ Time Frame: From baseline to active weight loss (at least 21 days of weight loss equivalent or greater than 0.5 pounds per week) and from baseline to weight loss plateau (after active weight loss, at least 21 days of halted weight loss, or +/- 0.25 pounds/week). ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Fred Hutch Cancer CenterSeattleWashington98109
University of Washington - South Lake UnionSeattleWashington98109

Find similar trials in Seattle, WA

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Fred Hutch Cancer Center· Seattle, WAUniversity of Washington - South Lake Union· Seattle, WA

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