Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study

Conditions

• Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma

Eligibility Criteria

Sex

FEMALE

Age

18 Years - N/A

Healthy Volunteers

Accepted

Interventions

• Non-Interventional Study — OTHER
  Non-interventional study

Study Details

This study evaluates how often women with throat (oropharyngeal) cancer or who have a partner with oropharyngeal cancer get anogenital infections with high risk, potentially cancer-causing types of human papilloma virus (HPV).

Key Dates

Start date

Nov 1, 2022

Status verified

Feb 2026

Primary completion

Nov 1, 2027

Completion

Nov 1, 2027

Study Design

Enrollment

154 participants (estimated)

Arms

• Arm: Observational
  Participants complete surveys, watch an educational video on HPV vaccination and undergo collection of blood and saliva samples on study. Patients also undergo cervical screening per standard of care and may receive a referral to gynecology if not up to date on anogenital screening.

Primary Outcome Measure

Incidence and prevalence of HPV(+) associated anogenital pathology in patients with newly diagnosed HPV(+)OPSCC [ Time Frame: Baseline (at enrollment) ]

Locations (1)

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