Biological Sex and CTEPH-related RV Dysfunction and Recovery (BIOSPHeRe)

Part of paid clinical trials in Murray, Utah.

Sponsor
Intermountain Health Care, Inc.
Study ID
NCT06105242
Status
Recruiting
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Conditions

  • CTEPH

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

1. To identify biological sex differences in baseline RV function in CTEPH 2. To identify biological sex differences in recovery of RV function after PTE surgery in CTEPH 3. To determine if sex hormone levels relate to RV function at CTEPH diagnosis and during recovery after PTE.

Key Dates

Start date
May 30, 2022
Status verified
Oct 2023
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
10 participants (estimated)

Arms

  • Arm: Retrospective Cohort Aim 1
    Aims 1 and 2 are retrospective and will be conducted with the same dataset, just at two different time points (at diagnosis of CTEPH and after PTE surgery). For simplicity, aims 1 and 2 will be combined into one section throughout the protocol.
  • Arm: Retrospective Cohort Aim 2
    Aims 1 and 2 are retrospective and will be conducted with the same dataset, just at two different time points (at diagnosis of CTEPH and after PTE surgery). For simplicity, aims 1 and 2 will be combined into one section throughout the protocol.
  • Arm: Prospective Cohort Aim 3
    Aim 3 is prospective and will enroll a distinct set of patients from Aim 1 and 2.

Primary Outcome Measure

Biosphere [ Time Frame: 1 year ]

Locations (1)

FacilityCityStateZIPSite coordinators
Intermountain Medical CenterMurrayUtah84107
Valerie Aston
[email protected]
801-507-4606
Darrin Applegate
[email protected]
801-507-4814
Meghan Cirulis, MD (PRINCIPAL_INVESTIGATOR)
Mark Dodson, MD (SUB_INVESTIGATOR)

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By research site
Intermountain Medical Center· Murray, UT

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