A Study of Neurodegeneration and Neuronal Fluctuations in Lewy Body Disease and Alzheimer's Disease

Part of paid clinical trials in Scottsdale, Arizona.

Sponsor
Mayo Clinic
Study ID
NCT06057909
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - 95 Years
Healthy Volunteers
Accepted

Interventions

  • Magnetic Resonance Imaging — DIAGNOSTIC_TEST
    Test that looks at the structure of the brain.
  • Electroencephalography — DIAGNOSTIC_TEST
    Non-invasive technique to measure brain waves
  • Electromyography — DIAGNOSTIC_TEST
    Technique to evaluate muscle activity

Study Details

The purpose of this research study is to investigate how the brain, memory, thinking, and motor behavior change both in individuals with movement and/or cognitive disorders, as well as healthy individuals. Researchers will look at measurements of memory, thinking, brain wave and muscle activity, daily functioning, and brain scans to learn more about brain disorders such as Alzheimer disease and Lewy body disease.

Key Dates

Start date
Apr 5, 2024
Status verified
Jan 2026
Primary completion
Jun 30, 2027
Completion
Jun 30, 2027

Study Design

Enrollment
90 participants (estimated)

Arms

  • Arm: Lewy Body Disease Group
    Subjects identified by their physician with a diagnosis of Lewy body disease will have a physical and neurological exam, MRI of brain, electroencephalography (EEG), and electromyography (EMG).
  • Arm: Alzheimer Disease Group
    Subjects identified by their physician with a diagnosis of Alzheimer will have a physical and neurological exam, MRI of brain, electroencephalography (EEG), and electromyography (EMG).
  • Arm: Healthy Control Group
    Subjects identified as a health individual will have a physical and neurological exam, MRI of brain, electroencephalography (EEG), and electromyography (EMG).

Primary Outcome Measure

Diffusion-weighted MRI (dMRI) [ Time Frame: Baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic ArizonaScottsdaleArizona85268
Shannon Chiu, MD
[email protected]

Find similar trials in Scottsdale, AZ

By condition
Alzheimer's disease
By specialty
NeurologyDementia careBrain disordersGeriatrics
By research site
Mayo Clinic Arizona· Scottsdale, AZ

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