AM vs PM Exercise Training
Part of paid clinical trials in East Lansing, Michigan.
- Sponsor
- Michigan State University
- Study ID
- NCT06042439
- Status
- Recruiting
Conditions
Eligibility Criteria
- Sex
- FEMALE
- Age
- 55 Years - 80 Years
- Healthy Volunteers
- Not accepted
Interventions
- 6 weeks of exercise training (Pre-training) — BEHAVIORALhandgrip and treadmill walking 4 days per week
- 6 weeks of exercise training (Post-training) — BEHAVIORALhandgrip and treadmill walking 4 days per week
Study Details
The treatment of high blood pressure, or hypertension, is multifaceted and can include pharmacological therapies (i.e., medications) and lifestyle modifications such as physical activity. Chronotherapy, which describes timing of a treatment with the body's daily rhythms, has recently been used with hypertension medications and has been shown to be effective at lowering blood pressure and reducing the risk of cardiovascular disease events. Specifically, taking medications in the evening was shown to be more effective than morning medication routines. Little information is available about the effectiveness of chronotherapy combined with exercise (i.e., planned physical activity) interventions in older adults with hypertension. The purpose of this study is to examine how exercise training performed in the morning and early evening affects blood pressure and other measures of blood vessel health in postmenopausal females with hypertension.
Key Dates
- Start date
- Jun 11, 2024
- Status verified
- Sep 2025
- Primary completion
- Jul 1, 2027
- Completion
- Jul 1, 2027
Study Design
- Enrollment
- 79 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- CROSSOVER
- Primary purpose
- TREATMENT
Arms
- Experimental: Morning (AM)Exercise starting before 10:01 AM
- Experimental: Evening (PM)Exercise starting after 3:59 PM
Primary Outcome Measure
Nocturnal systolic blood pressure (BP) [ Time Frame: 6 weeks ]
Central Contacts
- Jill Slade, PhD5178843351
- Katharine Currie, PhD517-432-4073
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Michigan State University | East Lansing | Michigan | 48824 |
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