AM vs PM Exercise Training

Part of paid clinical trials in East Lansing, Michigan.

Sponsor
Michigan State University
Study ID
NCT06042439
Status
Recruiting

Conditions

Eligibility Criteria

Sex
FEMALE
Age
55 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • 6 weeks of exercise training (Pre-training) — BEHAVIORAL
    handgrip and treadmill walking 4 days per week
  • 6 weeks of exercise training (Post-training) — BEHAVIORAL
    handgrip and treadmill walking 4 days per week

Study Details

The treatment of high blood pressure, or hypertension, is multifaceted and can include pharmacological therapies (i.e., medications) and lifestyle modifications such as physical activity. Chronotherapy, which describes timing of a treatment with the body's daily rhythms, has recently been used with hypertension medications and has been shown to be effective at lowering blood pressure and reducing the risk of cardiovascular disease events. Specifically, taking medications in the evening was shown to be more effective than morning medication routines. Little information is available about the effectiveness of chronotherapy combined with exercise (i.e., planned physical activity) interventions in older adults with hypertension. The purpose of this study is to examine how exercise training performed in the morning and early evening affects blood pressure and other measures of blood vessel health in postmenopausal females with hypertension.

Key Dates

Start date
Jun 11, 2024
Status verified
Sep 2025
Primary completion
Jul 1, 2027
Completion
Jul 1, 2027

Study Design

Enrollment
79 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Experimental: Morning (AM)
    Exercise starting before 10:01 AM
  • Experimental: Evening (PM)
    Exercise starting after 3:59 PM

Primary Outcome Measure

Nocturnal systolic blood pressure (BP) [ Time Frame: 6 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Michigan State UniversityEast LansingMichigan48824
Jill Slade, PhD
517-884-3351
Katharine Currie, PhD
517-432-4073

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