A Study of Investigational Tirzepatide (LY3298176) Doses in Participants With Type 2 Diabetes and Obesity

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
Eli Lilly and Company
Study ID
NCT06037252
Phase
PHASE2
Status
Active Not Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Tirzepatide — DRUG
    Administered SC
  • Placebo — DRUG
    Administered SC

Study Details

The main purpose of this study is to learn more about the safety and efficacy of investigational tirzepatide doses in participants with Type 2 diabetes and obesity that are already taking metformin. The study will last for about 89 weeks.

Key Dates

Start date
Sep 21, 2023
Status verified
Mar 2026
Primary completion
Jan 8, 2026
Completion
Oct 31, 2026

Study Design

Enrollment
414 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Tirzepatide High Dose 1
    Participants will receive tirzepatide subcutaneously (SC).
  • Experimental: Tirzepatide High Dose 2
    Participants will receive tirzepatide SC.
  • Active Comparator: Tirzepatide
    Participants will receive tirzepatide SC.
  • Placebo Comparator: Placebo
    Participants will receive placebo.

Primary Outcome Measure

Percent Change From Baseline in Body Weight [ Time Frame: Baseline (Week 0), Week 44 ]

Locations (20)

FacilityCityStateZIPSite coordinators
Medical Advancement Centers of ArizonaPhoenixArizona85044-
John Muir Physician Network Research CenterConcordCalifornia94520-
Care Access - SacramentoSacramentoCalifornia95831-
Care Access - AuroraAuroraColorado80012-
Chase Medical Research, LLCWaterburyConnecticut06708-
Retreat Medical ResearchMiamiFlorida33135-
American Research Centers of FloridaPembroke PinesFlorida33027-
Alta Pharmaceutical Research CenterNorcrossGeorgia30092-
AGILE Clinical Research Trials, LLCSandy SpringsGeorgia30328-
Northwestern UniversityChicagoIllinois60611-
Qualmedica Research, LLCEvansvilleIndiana47715-
Integrated Clinical Trial Services, Inc.West Des MoinesIowa50265-
Accellacare - Wilmington - 1917 Tradd CourtWilmingtonNorth Carolina28401-
Velocity Clinical Research, Mt. AuburnCincinnatiOhio45219-
Summit HeadlandsPortlandOregon97210-
Clinical Research Associates IncNashvilleTennessee37203-
Juno ResearchHoustonTexas77040-
Southern Endocrinology AssociatesMesquiteTexas75149-
Charlottesville Medical ResearchCharlottesvilleVirginia22911-
Northwest Clinical Research CenterBellevueWashington98007-

Find similar trials in Phoenix, AZ

By condition
Obesity / overweightType 2 diabetes
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Medical Advancement Centers of Arizona· Phoenix, AZJohn Muir Physician Network Research Center· Concord, CACare Access - Sacramento· Sacramento, CACare Access - Aurora· Aurora, COChase Medical Research, LLC· Waterbury, CTRetreat Medical Research· Miami, FL

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