tACS for Sensory Motor Recovery After Stroke

Part of paid clinical trials in Houston, Texas.

Sponsor
The University of Texas Health Science Center, Houston
Study ID
NCT06029062
Status
Recruiting
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Conditions

  • Motor Recovery

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • tACS Sham — DEVICE
    Sham tACS will applied to the brain through the scalp for 20 minutes.
  • tACS 10Hz — DEVICE
    10Hz tACS will applied to the brain through the scalp for 20 minutes.
  • tACS 20Hz — DEVICE
    20Hz tACS will applied to the brain through the scalp for 20 minutes.

Study Details

The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for motor recovery in stroke survivors.

Key Dates

Start date
Sep 1, 2025
Status verified
May 2026
Primary completion
Sep 30, 2027
Completion
Mar 31, 2028

Study Design

Enrollment
14 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Experimental: tACS Sham, tACS 10Hz, tACS 20Hz
    tACS Sham is a temporary non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp for up to 30 second, it is not designed to entrain neuronal activity into any external regulatory frequency patterns. tACS 10Hz is a 10Hz non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp or 20 or 40 minutes to entrain neuronal activity into 10Hz frequency patterns. tACS 20Hz is a 20Hz non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp for 20 or 40 minutes to entrain neuronal activity into 20Hz frequency patterns.
  • Experimental: HD-tACS 20Hz, HD-tACS 10Hz, HD-tACS Sham
    tACS Sham is a temporary non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp for up to 30 second, it is not designed to entrain neuronal activity into any external regulatory frequency patterns. tACS 10Hz is a 10Hz non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp or 20 or 40 minutes to entrain neuronal activity into 10Hz frequency patterns. tACS 20Hz is a 20Hz non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp for 20 or 40 minutes to entrain neuronal activity into 20Hz frequency patterns.
  • Experimental: HD-tACS 10Hz, HD-tACS 20Hz, HD-tACS Sham
    tACS Sham is a temporary non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp for up to 30 second, it is not designed to entrain neuronal activity into any external regulatory frequency patterns. tACS 10Hz is a 10Hz non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp or 20 or 40 minutes to entrain neuronal activity into 10Hz frequency patterns. tACS 20Hz is a 20Hz non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp for 20 or 40 minutes to entrain neuronal activity into 20Hz frequency patterns.

Primary Outcome Measure

Block and Box Test (BBT) of Motor functional test [ Time Frame: Change of BBT performance 5 minutes before and 5 minutes after the tACS intervention will be measured. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
The University of Texas Health Science CenterHoustonTexas77030
Sheng Li, MD, PhD
[email protected]
(713) 797-7125
Shengai Li, MS
[email protected]
713-797-7561

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By research site
The University of Texas Health Science Center· Houston, TX

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