Feasibility of Improving Glycemia With Heat Therapy to Prevent AD

Part of paid clinical trials in Kansas City, Kansas.

Sponsor
University of Kansas Medical Center
Study ID
NCT06023407
Status
Enrolling By Invitation

Conditions

Eligibility Criteria

Sex
ALL
Age
65 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Water Immersion Heat Therapy — OTHER
    10-weeks of 3 days per week in 1 of the 2 arms

Study Details

The investigators will determine if heat therapy can improve blood (Aim 1) and brain (Aim 2) glucose metabolism in cognitively healthy older adults (65+) who are at risk for AD. The investigators will also examine the degree to which changes in blood and brain glucose metabolism track together and explore several additional potential mechanisms that are critical to understanding the brain benefits of heat therapy (Aim 3). These aims will provide a comprehensive understanding of the impact of heat therapy on whole body metabolic function and brain health.

Key Dates

Start date
Feb 27, 2024
Status verified
Apr 2026
Primary completion
Oct 29, 2027
Completion
Mar 31, 2028

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Heat therapy Group
    40.5°C water
  • Sham Comparator: Thermoneutral Control Group
    36°C water

Primary Outcome Measure

HbA1C [ Time Frame: 10 weeks ]

Locations (1)

FacilityCityStateZIPSite coordinators
Univeristy of Kansas Medical CenterKansas CityKansas66160-

Find similar trials in Kansas City, KS

By condition
Alzheimer's disease
By specialty
NeurologyDementia careBrain disordersGeriatrics
By research site
Univeristy of Kansas Medical Center· Kansas City, KS

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