Electrophysiological Recordings from Deep Brain Stimulation Electrodes for Pain

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Study ID
NCT06019793
Status
Enrolling By Invitation

Conditions

  • Chronic Pain

Eligibility Criteria

Sex
ALL
Age
22 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • DBS for Chronic Pain — DEVICE
    Participants ill receive deep brain stimulation to relieve their chronic pain symptoms.

Study Details

Over the last 30 years, deep brain stimulation (DBS) has allowed tens of thousands of patients to receive relief of neurological symptoms that were refractory to standard medical treatment. Furthermore, by providing a rare window into the electrophysiological activity of the awake, human brain, DBS has facilitated invaluable advances in scientific understanding. These advances have then, in turn, allowed for further therapies to be developed for an ever growing population of patients that benefit from DBS therapy. This study hopes to add to this growing body of knowledge by implanting leads within, and recording from, the sensory thalamus and periaqueductal gray (PAG) in patients with chronic pain. Specifically, we hope to establish the long-term safety of DBS leads within the periaqueductal gray and sensory thalamus for the treatment of chronic pain. Furthermore, by recording from the electrodes of DBS patients implanted for treatment of their chronic pain, we hope to understand how the pain network responds to sensory stimuli and how DBS changes this response.

Key Dates

Start date
Jun 11, 2024
Status verified
Nov 2024
Primary completion
Dec 31, 2025
Completion
Dec 31, 2025

Study Design

Enrollment
50 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: DBS for Chronic Pain

Primary Outcome Measure

Safety of DBS for Chronic Pain as Assessed by Incidence of Treatment-Related Adverse Events [ Time Frame: 2 years ]

Locations (1)

FacilityCityStateZIPSite coordinators
Barrow Neurological InstitutePhoenixArizona85013-

Find similar trials in Phoenix, AZ

By research site
Barrow Neurological Institute· Phoenix, AZ

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