Imaging Based Uveitis Screening for Children With Juvenile Idiopathic Arthritis

Sponsor
Institute of Child Health
Study ID
NCT05984758
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
2 Years - 12 Years
Healthy Volunteers
Not accepted

Interventions

  • AS-OCT imaging — DIAGNOSTIC_TEST
    Image acquisition with the Optovue RTVue OCT and the Heidelberg Spectralis OCT2 machines
  • Slit lamp examination — DIAGNOSTIC_TEST
    SLE of anterior chamber

Study Details

This study seeks to describe, for children undergoing uveitis surveillance following a new diagnosis of juvenile idiopathic arthritis, the feasibility metrics of undertaking a randomised comparative study of routine slit lamp examination (SLE) versus imaging based (anterior segment optical coherence tomography, OCT) surveillance in order to inform the development of a larger multi-centre trial.

Key Dates

Start date
May 1, 2024
Status verified
Mar 2024
Primary completion
Jul 1, 2026
Completion
Oct 1, 2026

Study Design

Enrollment
80 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING

Arms

  • Active Comparator: Standard care
    Routine examination for uveitis with assessment of visual function followed by slit lamp examination
  • Experimental: ASOCT imaging
    Assessment of visual function followed by image acquisition with the Optovue RTVue OCT and the Heidelberg Spectralis OCT2 machines

Primary Outcome Measure

Proportion of patients who meet the eligibility criteria [ Time Frame: 18Months ]

Central Contacts

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