Assessment of Gait Adaptation Due to an Asymmetric Walking Protocol

Part of paid clinical trials in Storrs, Connecticut.

Sponsor
University of Connecticut
Study ID
NCT05968729
Status
Recruiting
Apply to this trial

Conditions

  • Anterior Cruciate Ligament Reconstruction

Eligibility Criteria

Sex
ALL
Age
18 Years - 30 Years
Healthy Volunteers
Not accepted

Interventions

  • Active Comparator: 0.25 m/s asymmetric session first — OTHER
    Participants will first perform an asymmetric walking trial where the between-limb gait speed difference is 0.25 m/s on day one. On the second day, participants will perform an asymmetric walking trial where the between-limb gait speed difference is 0.50 m/s.
  • Active Comparator: 0.50 m/s asymmetric session first — OTHER
    Participants will first perform an asymmetric walking trial where the between-limb gait speed difference is 0.50 m/s on day one. On the second day, participants will perform an asymmetric walking trial where the between-limb gait speed difference is 0.25 m/s.

Study Details

The purpose of this work is to conduct a comparative research-focused study to evaluate the effectiveness of how purposefully induced asymmetric walking protocols restore healthy, symmetric limb loading in individuals following post-anterior cruciate ligament reconstruction (ACLR) surgery. Additionally, computational modeling and machine learning to model knee loading in the clinic to determine the optimal asymmetric walking protocol to restore healthy gait in post-ACLR individuals.

Key Dates

Start date
Sep 1, 2022
Status verified
Jul 2025
Primary completion
Jul 31, 2027
Completion
Jul 31, 2027

Study Design

Enrollment
40 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Active Comparator: 0.25 m/s asymmetric session first
    Participants will perform three 15-minute sessions of walking with a 0.25 m/s asymmetric walking gait speed difference where one limb is set at 1.0 m/s and the other limb is set at 1.25 m/s. Each of these sessions will be followed by 5-minute de-adaptation sessions where they will perform a symmetric walking trial at 1.0 m/s.
  • Active Comparator: 0.50 m/s asymmetric walking session first
    Participants will perform three 15-minute sessions of walking with a 0.50 m/s asymmetric walking gait speed difference where one limb is set at 1.0 m/s and the other limb is set at 1.5 m/s. Each of these sessions will be followed by 5-minute de-adaptation sessions where they will perform a symmetric walking trial at 1.0 m/s.

Primary Outcome Measure

Change in Loading Rate [ Time Frame: Screening, Baseline, and Post-Treatment (immediately following the completion of the second session) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of ConnecticutStorrsConnecticut06269
Kristin Morgan, PhD
[email protected]
860-486-8118

Find similar trials in Storrs, CT

By research site
University of Connecticut· Storrs, CT

Related Studies