Improving Survival for Metastatic Lobular Breast Cancer (PLUMB Registry)

Part of paid clinical trials in San Diego, California.

Sponsor
University of California, San Francisco
Study ID
NCT05964504
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Blood Specimen — PROCEDURE
    Blood will be drawn via venipuncture

Study Details

This is a prospective observational registry for patients with invasive lobular carcinoma (ILC) of the breast. After the first 1cohort is enrolled, the collected data will be utilized to develop an ILC specific response assessment tool.

Key Dates

Start date
Dec 20, 2023
Status verified
Mar 2026
Primary completion
Feb 28, 2036
Completion
Feb 28, 2036

Study Design

Enrollment
12 participants (estimated)

Arms

  • Arm: Initial Cohort
    Up to 12 participants at each evaluation timepoint (approximately every 3-6 months to follow standard of care visits) will have up to 40 mL of blood drawn and distributed into 8 cell-free DNA Streck tubes, for plasma isolation, cell free DNA extraction, and ctDNA analysis. Blood for ctDNA analysis will be collected within +/- 14 days of whole body imaging studies which will occur when patients are scheduled for standard of care whole body imaging.

Primary Outcome Measure

Feasibility of registry [ Time Frame: Up to 2 years ]

Central Contacts

Locations (4)

FacilityCityStateZIPSite coordinators
University of California, San DiegoSan DiegoCalifornia92053
Rebecca Shatsky, MD (PRINCIPAL_INVESTIGATOR)
University of California, San FranciscoSan FranciscoCalifornia94122
Astrid Quirarte
[email protected]
415-476-8390
Rita Mukhtar, MD (PRINCIPAL_INVESTIGATOR)
A. Jo Chien, MD (PRINCIPAL_INVESTIGATOR)
Abramson Cancer CenterPhiladelphiaPennsylvania19104
Rachel Jankowitz, MD (PRINCIPAL_INVESTIGATOR)
MD Anderson Cancer CenterHoustonTexas77030
Jason Mouabbi, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in San Diego, CA

By condition
Breast cancer
By specialty
OncologyBreast oncologyWomen's health
By research site
University of California, San Diego· San Diego, CAUniversity of California, San Francisco· San Francisco, CAAbramson Cancer Center· Philadelphia, PAMD Anderson Cancer Center· Houston, TX

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