Thromboxane Function in Women With Endometriosis

Part of paid clinical trials in University Park, Pennsylvania.

Sponsor
Penn State University
Study ID
NCT05962034
Phase
PHASE4
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 45 Years
Healthy Volunteers
Accepted

Interventions

  • Aspirin — DRUG
    650 mg aspirin (Acetylsalicylic acid)
  • Placebo — OTHER
    placebo capsule

Study Details

The goal of this clinical trial is to compare neurovascular regulation in women with endometriosis and healthy women. The main questions it aims to answer are: * Do women with endometriosis have greater blood pressure and pain responses to a stimulus than healthy women? * Do women with endometriosis have greater platelet activity than healthy women? Participants will take aspirin and/or placebo and will: * perform hand grip exercise and cold pressor tests * undergo iontophoresis and blood draw Researchers will compare women with and without endometriosis to see if there is a difference in neurovascular regulation.

Key Dates

Start date
Jan 1, 2024
Status verified
May 2025
Primary completion
Aug 1, 2026
Completion
Aug 1, 2027

Study Design

Enrollment
96 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Aspirin
    one dose of aspirin
  • Placebo Comparator: Placebo
    Placebo pill

Primary Outcome Measure

blood pressure [ Time Frame: 1 day ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Noll LaboratoryUniversity ParkPennsylvania16802
Lacy Alexander, Ph.D.
[email protected]
814-867-1781

Find similar trials in University Park, PA

By condition
Endometriosis
By specialty
Women's healthFertility
By research site
Noll Laboratory· University Park, PA

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