Alternative Gingival De-Epithelialization Techniques

Part of paid clinical trials in Ann Arbor, Michigan.

Sponsor
University of Michigan
Study ID
NCT05947305
Status
Enrolling By Invitation

Conditions

  • Graft Complication
  • Recession, Gingival
  • Surgical Procedure, Unspecified
  • Wound Heal

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Surgical Blade — PROCEDURE
    Using a 15c blade to de-epithelialize the soft tissue extra-orally
  • Mucotome — PROCEDURE
    Using Megagen Mucotome to de-epithelialize the soft tissue intra-orally
  • Diamond Bur — PROCEDURE
    Using a surgical diamond bur to de-epithelialize the soft tissue intra-orally
  • Er:YAG Laser — PROCEDURE
    Using an Er:YAG Laser to de-epithelialize the soft tissue intra-orally

Study Details

The goal of this clinical trial is to compare different de-epithelialization methods in patients undergoing soft tissue augmentation surgery. The main questions it aims to answer are: • Which technique is superior for de-epithelialization in terms of remaining epithelium, wound healing of the donor site, and clinical outcomes?

Key Dates

Start date
Apr 4, 2024
Status verified
Jan 2026
Primary completion
Jun 30, 2026
Completion
Jul 1, 2026

Study Design

Enrollment
48 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Placebo Comparator: Surgical Blade
    A surgical blade will be used to de-epithelialize gum tissue during the subject's regularly scheduled dental surgery.
  • Experimental: Mucotome
    A mucotome will be used to de-epithelialize gum tissue during the subject's regularly scheduled dental surgery.
  • Experimental: Diamond Bur
    A diamond bur will be used to de-epithelialize gum tissue during the subject's regularly scheduled dental surgery.
  • Experimental: Er:YAG Laser
    A dental laser will be used to de-epithelialize gum tissue during the subject's regularly scheduled dental surgery.

Primary Outcome Measure

Histomorphometric Comparison [ Time Frame: After Day 0 (Baseline surgery) ]

Locations (1)

FacilityCityStateZIPSite coordinators
University of Michigan School of DentistryAnn ArborMichigan48109-

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By research site
University of Michigan School of Dentistry· Ann Arbor, MI

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