Cognitive Training in the Virtual Reality Setting With Children Undergoing Radiotherapy for Brain Tumors

Conditions

• Brain Tumor

Eligibility Criteria

Sex

ALL

Age

8 Years - 22 Years

Healthy Volunteers

Not accepted

Interventions

• Cognitive training via iPad — OTHER
  Participants will complete five sessions of the Cogmed training program on an iPad. Participants will complete sessions over the course of one to two weeks while on campus for radiotherapy. Each session will take place in the Psychology Clinic and consist of 15 to 20 minutes of Cogmed training.
• Cognitive training via virtual reality — OTHER
  Participants will complete five sessions of the Cogmed training program within virtual reality. Participants will complete sessions over the course of one to two weeks while on campus for radiotherapy. Each session will take place in the Psychology Clinic and consist of 15 to 20 minutes of Cogmed training.

Study Details

The objective of this study is to estimate the feasibility and acceptability of cognitive training in the virtual reality setting with children undergoing radiotherapy for brain tumors. To achieve this goal, the investigators plan to study children undergoing radiotherapy for brain tumors randomly assigned to cognitive training administered via an iPad or virtual reality. Both groups will also participate in cognitive testing and exams using functional near infrared spectroscopy (fNIRS) pre- and post-intervention. The questions to be investigated are: 1. Will cognitive training via virtual reality be feasible and acceptable for children undergoing radiotherapy for brain tumors as indicated by participation rates, adherence and frequency of side effects? 2. Will cognitive training via virtual reality provide neurocognitive benefits? 3. Will there be predictable changes in brain activity as measured by neuroimaging? Findings from this study will be used to develop a larger, definitive trial with direct potential to improve cognitive outcomes for children treated for cancer using a safe and effective alternative to desktop- or laptop-based computerized cognitive interventions with great promise for improving quality of life.

Key Dates

Start date

Jun 22, 2023

Status verified

Apr 2026

Primary completion

Mar 31, 2027

Completion

Mar 31, 2027

Study Design

Enrollment

45 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Arms

• Active Comparator: IPad Cogmed Training
  The investigator will be randomizing participants to complete Cogmed training on an iPad.
• Experimental: Virtual Reality Cogmed Training
  The investigator will be randomizing participants to complete Cogmed training in Virtual Reality.

Primary Outcome Measure

Participation Rate [ Time Frame: After approach for enrollment, an average of 3 weeks after starting radiation therapy ]

Central Contacts

• Heather Conklin, PhD
  888-226-4343
  [email protected]

Locations (1)

Find similar trials in Memphis, TN

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