Respiratory Support and Treatment for Efficient and Cost-Effective Care

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
Christopher Horvat
Study ID
NCT05909566
Status
Recruiting
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Conditions

  • Bronchiolitis

Eligibility Criteria

Sex
ALL
Age
N/A - 2 Years
Healthy Volunteers
Not accepted

Interventions

  • Clinical Decision Support (CDS) — OTHER
    Education to front line clinicians and staff on standardized implementation and weaning of HHFNC and standardized assessments of patient work of breathing. HHFNC implementation and weaning strategies will be based on age-specific practices recommended by the American Academy of Pediatrics. Education will be undertaken by dedicated clinical educators.
  • HHFNC Weaning — DEVICE
    Wean patient off oxygen and flow as oxygenation and work of breathing improves.

Study Details

This project aims to answer the essential questions about the management of acute, pediatric respiratory illness, accelerate recovery from these all-too-common diseases, curb unnecessary costs of care, and demonstrate UPMC Children's Hospital of Pittsburgh's capabilities as the premier, world-class leader in the arena of pediatric learning healthcare systems. REST EEC will focus on the question of whether clinical decision support (CDS) facilitates the standardization of the initiation and weaning of heated high flow nasal cannula (HHFNC) for bronchiolitis.REST EEC will focus on whether the application of CDS improves adherence to a standardized guideline and leads to improved patient-centered outcomes.

Key Dates

Start date
Oct 25, 2023
Status verified
Jul 2025
Primary completion
Apr 30, 2026
Completion
May 31, 2026

Study Design

Enrollment
198 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: HHFNC + Clinical decision Support
    Standardized HHFNC weaning coupled with clinical decision support consisting of electronic record embedded reminders to the clinical team to wean HHFNC
  • Active Comparator: HHFNC Weaning
    Team does not receive clinical decision support reminders to wean the HHFNC

Primary Outcome Measure

HFNC duration [ Time Frame: Timeframe consists of a start time of either randomization or the last documentation of positive pressure ventilation (whichever is later) and the last documentation of HFNC in the electronic flowsheet, up to 30 days ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UPMC Children's Hospital of PittsburghPittsburghPennsylvania15224
Christopher Horvat, MD
[email protected]
4126925298

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By research site
UPMC Children's Hospital of Pittsburgh· Pittsburgh, PA

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