Trifecta-Lung cfDNA-MMDx Study

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
University of Alberta
Study ID
NCT05837663
Status
Recruiting
Apply to this trial

Conditions

  • Lung Transplantation

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

Demonstrate the relationship between dd-cfDNA levels and HLA antibodies in blood transplant recipient and Demonstrate the Molecular Microscope® (MMDx) Diagnostic System results in indication and protocol biopsies from lung transplants.

Key Dates

Start date
Nov 1, 2023
Status verified
Jun 2026
Primary completion
Nov 30, 2027
Completion
Dec 31, 2028

Study Design

Enrollment
600 participants (estimated)

Primary Outcome Measure

Calibration of Prospera® test for T cell mediated rejection [ Time Frame: 18 months ]

Central Contacts

Locations (12)

FacilityCityStateZIPSite coordinators
St. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLTPhoenixArizona85013
Chanti F Smith
[email protected]
Rajat Walia, MD (PRINCIPAL_INVESTIGATOR)
Division of Pulmonary, Critical Care and Sleep Medicine, University of Florida, College of MedicineGainesvilleFlorida32610
Duncan Lewis, BS, CCRP
[email protected]
Amir Emtiazjoo, MD, MSc (PRINCIPAL_INVESTIGATOR)
Christina Eagan, MD (SUB_INVESTIGATOR)
Hiren Mehta, MD (SUB_INVESTIGATOR)
Mayo Clinic Florida, 4500 San Pablo RdJacksonvilleFlorida32224
Stacey N Caster
[email protected]
Remzi Bag, MD (PRINCIPAL_INVESTIGATOR)
USF Health, Morsani College of Medicine, 12901 Bruce B. Downs Blvd. MDC40TampaFlorida33612
Gabriel Parker, MA
[email protected]
Ishna Poojary-Hohman, MD (PRINCIPAL_INVESTIGATOR)
Indiana University Methodist Hospital 1812 N. Capitol Ave Suite W131LIndianapolisIndiana46202
Erin Sartoris, RN
[email protected]
Nikki Smith, MD (PRINCIPAL_INVESTIGATOR)
Johns Hopkins Interventional Pulmonology, Sheikh Zayed Tower, Room 7125L, 1800 Orleans StreetBaltimoreMaryland21287
Jeffrey Thiboutot, MD MHS (PRINCIPAL_INVESTIGATOR)
Division of Pulmonary, Allergy & Critical Care Medicine Columbia University Irving Medical CenterNew YorkNew York10032
Shreena Patel, MPH, LPN
[email protected]
Kemarut Laothmatas, MD (PRINCIPAL_INVESTIGATOR)
The Ohio State University Wexner Medical Center, 410 W 10th AveColumbusOhio43210
Erwin Cooper
[email protected]
Justin Rosenheck, DO (PRINCIPAL_INVESTIGATOR)
BAYLOR SCOTT & WHITE RESEARCH INSTITUTE , 3409 Worth StreetDallasTexas75246
Felicia Padilla
[email protected]
214-820-1771
Todd Grazia, MD (SUB_INVESTIGATOR)
Samir Kumar, MD MBA (PRINCIPAL_INVESTIGATOR)
UT Southwestern Medical Center, 5939 Harry Hines Blvd.DallasTexas75390
Irina L Timofte, MD
[email protected]
Irina L Timofte, MD (PRINCIPAL_INVESTIGATOR)
Houston Methodist Lung Transplant Center, 6550 Fannin St., SM1001HoustonTexas77030
Darrel W Cleere
[email protected]
Howard J Huang, MD (PRINCIPAL_INVESTIGATOR)
UT Health San Antonio 7703 Floyd Curl Drive, MSC: 7858San AntonioTexas78229
Renee Walruff, BS
[email protected]
Lara Jones, DO (PRINCIPAL_INVESTIGATOR)

Find similar trials in Phoenix, AZ

By research site
St. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLT· Phoenix, AZDivision of Pulmonary, Critical Care and Sleep Medicine, University of Florida, College of Medicine· Gainesville, FLMayo Clinic Florida, 4500 San Pablo Rd· Jacksonville, FLUSF Health, Morsani College of Medicine, 12901 Bruce B. Downs Blvd. MDC40· Tampa, FLIndiana University Methodist Hospital 1812 N. Capitol Ave Suite W131L· Indianapolis, INJohns Hopkins Interventional Pulmonology, Sheikh Zayed Tower, Room 7125L, 1800 Orleans Street· Baltimore, MD

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