Omega-3 Fatty Acids as Regulators of Brown Adipose Tissue During Cold Exposure

Part of paid clinical trials in Bloomington, Indiana.

Sponsor
Indiana University
Study ID
NCT05822141
Status
Recruiting
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Conditions

  • Cold Exposure

Eligibility Criteria

Sex
ALL
Age
18 Years - 40 Years
Healthy Volunteers
Accepted

Interventions

  • Fish Oil — DIETARY_SUPPLEMENT
    For 12 weeks subjects will ingest 6 capsules per day of fish oil (7.8 g/day total omega--3 fatty acids: 3.75 g/day EPA and 1.5 g/day DHA)
  • Placebo — DIETARY_SUPPLEMENT
    For 12 weeks subjects will ingest 6 capsules per day of olive oil (each capsule contains 990 mg of olive oil)

Study Details

This clinical trial will assess the whether fish oil supplementation can modulate brown fat activation, shivering, thermal comfort and skin blood flow during cold exposure.

Key Dates

Start date
Jun 12, 2023
Status verified
May 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Fish Oil (Omega-3 Fatty Acids)
    15 subjects will ingest 6 capsules of fish oil of per day for 12 weeks
  • Placebo Comparator: Olive Oil
    15 subjects will ingest 6 capsules of olive oil per day for 12 weeks

Primary Outcome Measure

Core Temperature: [ Time Frame: 125 minutes ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Human Perfromance Lab, Indiana UniversityBloomingtonIndiana47405
Timothy Mickleborough, PhD
[email protected]

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By research site
Human Perfromance Lab, Indiana University· Bloomington, IN

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