Investigation of Mohs Surgical Margins Using Two Photon Microscopy

Part of paid clinical trials in Victor, New York.

Sponsor
University of Rochester
Study ID
NCT05814900
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Two photon microscopy imaging — DEVICE
    Excised tissues will be imaged with two photon microscopy

Study Details

The goal of this clinical trial is to compare the use of two photon fluorescence microscopy for detecting residual basal cell carcinoma during Mohs surgery. The main question it aims to answer is: • How similar are diagnosis of surgical margins to on two photon fluorescence microscopy compared to frozen section histology

Key Dates

Start date
Jun 20, 2023
Status verified
Mar 2026
Primary completion
Jun 19, 2025
Completion
Jun 19, 2025

Study Design

Enrollment
135 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Experimental: TPFM imaging of surgical margins
    Patients will be imaged with TPFM

Primary Outcome Measure

Agreement Between Frozen Sections and Two Photon Fluorescence Microscopy on Mohs Margins [ Time Frame: During Mohs surgery, typically less than 60 minutes ]

Locations (1)

FacilityCityStateZIPSite coordinators
Rochester Dermatologic SurgeryVictorNew York14654-

Find similar trials in Victor, NY

By condition
Skin cancer
By specialty
OncologySkin cancerDermatology
By research site
Rochester Dermatologic Surgery· Victor, NY

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