Optimizing PrEP Uptake and Adherence Among Male Sex Workers

Part of paid clinical trials in Los Angeles, California.

Sponsor
Brown University
Study ID
NCT05736614
Status
Recruiting
Apply to this trial

Conditions

  • Prevention

Eligibility Criteria

Sex
MALE
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Stage 1 Strength Based Case Management (SBCM) Condition — BEHAVIORAL
    Intervention participants will receive a trained SBCM to motivate, support, and assist in linkage to PrEP prescribers to help facilitate obtaining PrEP medication to initiate treatment.
  • Stage 2 PrEPare for Work Intervention Condition — BEHAVIORAL
    Intervention participants will receive 1-on-1 adherence counseling and personalized daily text messaging reminders to increase PrEP adherence. Intervention participants will undergo three adherence intervention sessions (once per week for 3 weeks) with interventionist.

Study Details

"PrEPare for Work" is a randomized controlled trial (RCT) whose goal is to test the efficacy of a behavioral intervention (Short Title: PrEPare for Work) in improving PrEP uptake, adherence, and persistence among male sex workers (MSW)

Key Dates

Start date
Nov 3, 2022
Status verified
May 2025
Primary completion
Jun 30, 2026
Completion
Jun 30, 2026

Study Design

Enrollment
500 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • No Intervention: Stage 1 Standard of Care (SOC) Control Condition
    SOC participants will receive an informational pamphlet about the PrEP as a form of HIV prevention and referrals to local PrEP Prescribers.
  • Experimental: Stage 1 Strength Based Case Management (SBCM) Condition
    Intervention participants will receive a trained SBCM to motivate, support, and assist in linkage to PrEP prescribers to help facilitate obtaining PrEP medication to initiate treatment.
  • No Intervention: Stage 2 SOC Control Condition
    Research staff will show a brief video that describes what PrEP is and how it works to prevent HIV via sexual and injection transmission. Participants will continue to see their PrEP prescriber for routine clinical care.
  • Experimental: Stage 2 PrEPare for Work Intervention Condition
    Intervention participants will receive 1-on-1 adherence counseling and personalized daily text messaging reminders to increase PrEP adherence. Intervention participants will undergo three adherence intervention sessions (once per week for 3 weeks) with interventionist.

Primary Outcome Measure

Stage one: PrEP initiation [ Time Frame: 2-month post Stage 1 randomization ]

Central Contacts

Locations (5)

FacilityCityStateZIPSite coordinators
UCLA Fielding School of Public HealthLos AngelesCalifornia90095
Brown University School of Public HealthProvidenceRhode Island02912
Vanessa Silva
Vanessa Silva <[email protected]>
6178988486
Katie Biello, PhD
[email protected]
401 863 3082
Open Door HealthProvidenceRhode Island02907
Philip Chan, MD
[email protected]
1-401-648-4700
Project Weber/RENEWProvidenceRhode Island02907
Colleen Daley Ndoye
[email protected]
(401) 383-4888
The Miriam HospitalProvidenceRhode Island02906
Philip A Chan, MD
[email protected]
401-793-2928

Find similar trials in Los Angeles, CA

By research site
UCLA Fielding School of Public Health· Los Angeles, CABrown University School of Public Health· Providence, RIOpen Door Health· Providence, RIProject Weber/RENEW· Providence, RIThe Miriam Hospital· Providence, RI

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