Exercise for Cognitive Excellence in Parkinson's Disease

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT05720468
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
40 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Exercise — OTHER
    Combined endurance and resistance exercise training
  • No Exercise — OTHER
    Continue usual level of physical activity; option to participate in exercise training program after 26-week intervention period

Study Details

This study will evaluate the safety and feasibility of a home-based, virtually-supervised, combined high intensity endurance and resistance training program in people with Parkinson's disease. It will also evaluate the effects of exercise on cognition and underlying exercise-related biological markers (biomarkers).

Key Dates

Start date
Jul 20, 2023
Status verified
Mar 2026
Primary completion
Dec 1, 2026
Completion
Dec 1, 2026

Study Design

Enrollment
32 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Exercise
    Participants randomized to the exercise group will receive 26 weeks of home-based, combined endurance and resistance training program under guidance and virtual supervision from exercise trainers. Exercise will be performed 5 days per week, with 3 days of endurance training using treadmill and 2 days of resistance training.
  • Placebo Comparator: Waitlist Control Group
    The control group will continue usual level of physical activity the participants were doing prior to enrollment in the study. At the end of the 26 week study period, participants will be offered the chance to participate in the same home-based, combined endurance and resistance training program.

Primary Outcome Measure

Average percent heart rate maximum (HR max) [ Time Frame: From weeks 5-26, every exercise session ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California San FranciscoSan FranciscoCalifornia94518
Nijee Luthra, MD, PhD
[email protected]
(415) 502-2960
Nijee Luthra, MD, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in San Francisco, CA

By condition
Parkinson's disease
By specialty
NeurologyBrain disorders
By research site
University of California San Francisco· San Francisco, CA

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