Retrospective Review of Esophageal Cancer at MSKCC

Part of paid clinical trials in New York, New York.

Sponsor
Memorial Sloan Kettering Cancer Center
Study ID
NCT05706558
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Esophagectomy — PROCEDURE
    Esophagectomy

Study Details

Residual tumor at the proximal or distal margin after esophagectomy is a known prognostic factor for poor survival outcomes in patients with esophageal cancer; however, the significance of the circumferential resection margin (CRM) remains controversial. In this study, the investigators sought to evaluate the prognostic significance of the CRM in patients with esophageal cancer undergoing resection.

Key Dates

Start date
Dec 13, 2016
Status verified
Mar 2026
Primary completion
Feb 28, 2027
Completion
Feb 28, 2027

Study Design

Enrollment
4,000 participants (estimated)

Arms

  • Arm: Circumferential resection margin (CRM)
    Participants will have a diagnosis of esophageal carcinoma and residual tumor \>1 mm from the CRM
  • Arm: Circumferential resection margin (CRM)-close
    Participants will have a diagnosis of esophageal carcinoma and residual tumor \>0-1 mm from the CRM
  • Arm: Circumferential resection margin (CRM)+
    Participants will have a diagnosis of esophageal carcinoma and residual tumor at the surgical CRM

Primary Outcome Measure

. Preoperative variables associated with overall survival and progression-free survival (measured from date of surgery) [ Time Frame: Up to 2 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New YorkNew York10065
Daniela Molena, MD
212-639-3870

Find similar trials in New York, NY

By condition
Esophageal cancer
By specialty
OncologyGI oncology
By research site
Memorial Sloan Kettering Cancer Center (All Protocol Activities)· New York, NY

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