3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial

Part of paid clinical trials in Houston, Texas.

Sponsor
M.D. Anderson Cancer Center
Study ID
NCT05674396
Phase
PHASE2
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Stereotactic body radiotherapy — RADIATION
    Participants will receive radiation as per the schedule discussed with the study doctor.
  • Traditional Palliation — RADIATION
    Participants will receive radiation as per the schedule discussed with the study doctor.

Study Details

To learn if it is effective to use advanced radiation treatment techniques (stereotactic radiation or "SBRT") to safely deliver a strong dose of radiation to your tumor in a shorter period of time than would typically be feasible with traditional methods.

Key Dates

Start date
Jun 30, 2023
Status verified
Feb 2026
Primary completion
Sep 30, 2027
Completion
Sep 30, 2027

Study Design

Enrollment
108 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Traditional Palliation
    Participant will be randomized to standard radiation
  • Experimental: Stereotactic body radiotherapy (SBRT)
    Participants will be randomized to receive (SBRT) Stereotactic body radiotherapy.

Primary Outcome Measure

M. D. Anderson Symptom Inventory - Head & Neck (MDASI-HN) Questionnaires [ Time Frame: through study completion; an average of 1 year. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
M D Anderson Cancer CenterHoustonTexas77030
Jay Reddy, MD, PHD
[email protected]
832-750-2924
Jay Reddy, MD, PHD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Houston, TX

By condition
Head and neck cancer
By specialty
OncologyENT
By research site
M D Anderson Cancer Center· Houston, TX

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