Study of Transcranial Direct Current Stimulation to Treat Epilepsy

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT05673915
Status
Recruiting
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Conditions

  • Focal Epilepsy
  • Generalized Onset Epilepsy
  • Sleep-related Epileptic Encephalopathy

Eligibility Criteria

Sex
ALL
Age
6 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • ActivaDose II 0.1 mA transcranial direct current stimulation (tDCS) — DEVICE
    Stimulation setting 0.1 mA daily for a 2-month period. Each daily treatment will last for approximately 30 minutes.
  • ActivaDose II 2.0 mA transcranial direct current stimulation (tDCS) — DEVICE
    Stimulation setting 2.0 mA daily for a 2-month period. A Each daily treatment will last for approximately 30 minutes.

Study Details

The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic seizures.

Key Dates

Start date
Apr 12, 2023
Status verified
Jan 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
30 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Experimental: tDCS Treatment A (Low Amplitude)
    Subjects with focal epilepsy that is not well-controlled on anti-seizure medications will receive 2 different treatments periods, each lasting 2 months, of transcranial direct current stimulation (tDCS). The initial treatment stimulation will be completed during the first 2-months.
  • Experimental: tDCS Treatment B (High Amplitude)
    Subjects with focal epilepsy that is not well-controlled on anti-seizure medications will receive 2 different treatments periods, each lasting 2 months, of transcranial direct current stimulation (tDCS). The last treatment stimulation will be completed during the following 2-months.

Primary Outcome Measure

Seizure Count [ Time Frame: 2 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic MinnesotaRochesterMinnesota55905-

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By research site
Mayo Clinic Minnesota· Rochester, MN

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