DREAM: Double Lung Transplant REgistry Aimed for Lung-limited Malignancies

Part of paid clinical trials in Chicago, Illinois.

Sponsor
Northwestern University
Study ID
NCT05671887
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Double Lung Transplantation — PROCEDURE
    To evaluate outcomes among patients who undergo lung transplantation for treatment of a select group of medically refractory cancers affecting the lungs alone without extrapulmonary nodal and distant metastasis.

Study Details

This is a prospective observational registration trial for patients who undergo lung transplantation for the treatment of the select groups of medically refractory cancers affecting the lungs alone without extrapulmonary nodal and distant metastasis.

Key Dates

Start date
Nov 16, 2022
Status verified
Nov 2024
Primary completion
Nov 30, 2032
Completion
Nov 30, 2032

Study Design

Enrollment
125 participants (estimated)

Arms

  • Arm: Cohort A: Primary lung cancers
    \- Examples include invasive mucinous/non-mucinous non-small cell lung cancers and multifocal carcinomas
  • Arm: Cohort B: Metastatic cancers to the lung only
    \- Examples include germ cell tumors, head \& neck tumors, colorectal tumors, renal cell tumors
  • Arm: Cohort C: Respiratory failure with a history of cancer in the last 5 years
    \- Examples include, but not limited to interstitial lung disease (ILD), pulmonary fibrosis (idiopathic or secondary), advanced chronic obstructive pulmonary disease (COPD), bronchiectasis, emphysema, cystic fibrosis (CF), emphysema due to alpha-1 antitrypsin deficiency, and pulmonary arterial hypertension (PAH)

Primary Outcome Measure

overall survival (OS) rate [ Time Frame: 30-day ]

Central Contacts

  • Lung Transplant Thoracic Surgery, Canning Thoracic Institute (Northwestern Memorial Hospital)
    312-695-5864
    [email protected]
  • Liam Il-Young Chung, MD MPH
    312-472-6245
    [email protected]

Locations (1)

FacilityCityStateZIPSite coordinators
Thoracic Surgery, Canning Thoracic Institute (Northwestern Memorial Hospital)ChicagoIllinois60611
Lung Transplant Thoracic Surgery, Canning Thoracic Institute (Northwestern Memorial Hospital)
[email protected]
312-695-5864
Liam Il-Young Chung, MD MPH
[email protected]
312-472-6245
Young Chae, MD MPH MBA
Ankit Bharat, MD
Rade Tomic, MD

Find similar trials in Chicago, IL

By condition
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By specialty
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By research site
Thoracic Surgery, Canning Thoracic Institute (Northwestern Memorial Hospital)· Chicago, IL

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