GABA Biomarkers in Dravet Syndrome

Part of paid clinical trials in Fort Worth, Texas.

Sponsor
Cook Children's Health Care System
Study ID
NCT05651204
Status
Recruiting
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Conditions

  • Dravet Syndrome

Eligibility Criteria

Sex
ALL
Age
N/A - 18 Years
Healthy Volunteers
Accepted

Interventions

  • GABA Blood Level — DIAGNOSTIC_TEST
    Blood specimens will be collected by a registered phlebotomist according to hospital's specimen collection procedures.

Study Details

This study will non-invasively obtain levels of GABA in the brain of children with SCN1A+DS and neurodeveloping children through evoked and induced cortical responses, correlate them with the BOLD responses, and with the levels of GABA in their blood.

Key Dates

Start date
Sep 8, 2022
Status verified
Dec 2022
Primary completion
Sep 8, 2024
Completion
Sep 8, 2027

Study Design

Enrollment
36 participants (estimated)

Arms

  • Arm: Dravet
  • Arm: Age-Matched Control

Primary Outcome Measure

GABA Blood Level [ Time Frame: Up to 30 minutes ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Cook Children's Medical CenterFort WorthTexas76104
Sabrina Shandley, PhD
[email protected]
682-885-3437
Laurie Bailey, PhD
[email protected]
(682) 885-2488
Christos Papadelis, PhD (PRINCIPAL_INVESTIGATOR)

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Cook Children's Medical Center· Fort Worth, TX

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