A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With EFP; Cellulite (Stage 1)

Part of paid clinical trials in Encino, California.

Sponsor
Caliway Biopharmaceuticals Co., Ltd.
Study ID
NCT05632926
Phase
PHASE2
Status
Completed

Conditions

  • Cellulite

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 64 Years
Healthy Volunteers
Not accepted

Interventions

  • 40 mg CBL-514 — DRUG
    CBL-514 will be administered at the raised area of cellulite.
  • 60 mg CBL-514 — DRUG
    CBL-514 will be administered at the raised area of cellulite.
  • 80 mg CBL-514 — DRUG
    CBL-514 will be administered at the raised area of cellulite.

Study Details

The Stage 1 of this phase 2 study is an open-label single ascending dose (SAD) study to assess the efficacy and safety of CBL-514 in participants with Edematous Fibrosclerotic Panniculopathy (EFP) cellulite.

Key Dates

Start date
Jan 9, 2023
Status verified
Jun 2023
Primary completion
May 3, 2023
Completion
May 3, 2023

Study Design

Enrollment
12 participants (actual)
Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: CBL-514 40mg
  • Experimental: CBL-514 60mg
  • Experimental: CBL-514 80mg

Primary Outcome Measure

Evaluation of the improvement of edematous fibrosclerotic panniculopathy (EFP) measured by cellulite severity scale from baseline following administration of 1 course of CBL-514. [ Time Frame: Up to 4 weeks from treatment visit ]

Locations (2)

FacilityCityStateZIPSite coordinators
Investigational Site 1EncinoCalifornia91436-
Investigational Site 2New YorkNew York10022-

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