Endocrine Therapy-Induced Alopecia in Postmenopausal and Premenopausal Female Breast Cancer Patients

Conditions

• Breast Carcinoma

Eligibility Criteria

Sex

FEMALE

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Electronic Health Record Review — OTHER
  Ancillary studies
• Questionnaire Administration — OTHER
  Complete alopecia questionnaires
• Survey Administration — OTHER
  Complete alopecia surveys

Study Details

This study evaluates endocrine therapy-induced alopecia among postmenopausal and premenopausal female patients with breast cancer. Alopecia is one of the most feared side effects of cancer-directed therapy, causing distress in women starting treatment for breast cancer. While alopecia is a well-known side effect of many chemotherapy drugs, it has also been reported by women undergoing endocrine therapy. Despite the frequent reports of alopecia related to endocrine therapy, hair loss is rarely reported as a side effect of endocrine therapy and the exact characterization of alopecia is not well understood. By having postmenopausal and premenopausal breast cancer patients describe their hair loss symptoms experienced while undergoing endocrine therapy, researchers may be able to better characterize the incidence, timing, duration, and severity of alopecia and whether the different types of endocrine therapy cause more or less trouble in this regard.

Key Dates

Start date

Jul 6, 2022

Status verified

Apr 2026

Primary completion

Jun 30, 2028

Completion

Jun 30, 2028

Study Design

Enrollment

170 participants (estimated)

Arms

• Arm: Observational (alopecia questionnaires and surveys)
  Patients complete alopecia questionnaires and surveys and have medical records reviewed on study.

Primary Outcome Measure

Estimation and characterization of patient-reported treatment-emergent alopecia within and across the cohorts [ Time Frame: Up to study completion; up to two years ]

Locations (23)

Find similar trials in Albert Lea, MN

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