Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target)
- Sponsor
- Jena University Hospital
- Study ID
- NCT05587621
- Status
- Not Yet Recruiting
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Conditions
- LDL-cholesterol
- Non-ST Elevation Myocardial Infarction
- ST Elevation Myocardial Infarction
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- statins, ezetimibe, bempedoic acid, evolocumab, alirocumab, inclisiran — DRUGdietary advice for low cholesterol food
Study Details
Intensive Lipid-Lowering Therapy guided by a cloud-based Software System (CLIMEDO GmbH) improves (European Society of Cardiolofgy/European Atherosclerosis Society) ESC/EAS-guideline recommended LDL-cholesterol target attainment and adherence in patients with ST-Elevation Myocardial (STEMI) and Non-ST-Elevation Myocardial Infarctions (NSTEMI).
Key Dates
- Start date
- Apr 1, 2024
- Status verified
- Sep 2023
- Primary completion
- Apr 30, 2026
- Completion
- Dec 31, 2026
Study Design
- Enrollment
- 300 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- PREVENTION
Arms
- Active Comparator: Cloud-based softwarecloud-based software system (CLIMEDO GmbH) will support patients in ESC/EAS LDL-C target attainment (\< 55mg/dl/1.4 mol/L)
- Placebo Comparator: Standard CarePatients will be treated by general practitioners (GPs) after hospital discharge. The discharge letter will recommend ESC/EAS dyslipidemia LDL-cholesterol targets (\< 55mg/dl/1.4 mol/L)
Primary Outcome Measure
LDL-C [ Time Frame: 6 months ]
Central Contacts
- Oliver Weingärter, MD036419324521
- Franz Härtel, MD
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