A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity

Part of paid clinical trials in Gilbert, Arizona.

Sponsor
Eli Lilly and Company
Study ID
NCT05556512
Phase
PHASE3
Status
Active Not Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
40 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Tirzepatide — DRUG
    Administered SC
  • Placebo — DRUG
    Administered SC

Study Details

This study will investigate the effect of tirzepatide on the reduction of morbidity and mortality in adults living with obesity and provide additional evidence for the potential clinical benefits of tirzepatide in this population.

Key Dates

Start date
Oct 11, 2022
Status verified
Jan 2026
Primary completion
Oct 31, 2027
Completion
Oct 31, 2027

Study Design

Enrollment
15,374 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Tirzepatide
    Participants will receive escalated doses of tirzepatide subcutaneously (SC) up to a maximum tolerated dose.
  • Placebo Comparator: Placebo
    Participants will receive tirzepatide matched placebo.

Primary Outcome Measure

Time to First Occurrence of Any Component Event of Composite (All-Cause Death, Nonfatal Myocardial Infarction (MI), Nonfatal Stroke, Coronary Revascularization, or Heart Failure Events) [ Time Frame: Up to 5 Years ]

Locations (165)

FacilityCityStateZIPSite coordinators
Prime Medical Group, LLC dba Gilbert Center for Family Medicine, LLCGilbertArizona85296-
Aventiv ResearchMesaArizona85206-
Elite Clinical StudiesPhoenixArizona85018-
Pima HeartTucsonArizona85741-
KLR Business Group, Inc. dba Arkansas Clinical ResearchLittle RockArkansas72205-
Smart Cures Clinical ResearchAnaheimCalifornia92806-
Kidney & Hypertension Center - Apple ValleyApple ValleyCalifornia92307-
Hope Clinical Research, Inc.Canoga ParkCalifornia91303-
John Muir Physician Network Research CenterConcordCalifornia94520-
Neighborhood Healthcare Institute of HealthEscondidoCalifornia92025-
HB Clinical Trials - Fountain ValleyFountain ValleyCalifornia92708-
Valiance Clinical ResearchHuntington ParkCalifornia90255-
Scripps Whittier Diabetes InstituteLa JollaCalifornia92037-
Velocity Clinical Research, San DiegoLa MesaCalifornia91942-
First Valley Medical GroupLancasterCalifornia93534-
Long Beach Clinical TrialsLong BeachCalifornia90806-
Infinity Clinical Research - NorcoNorcoCalifornia92860-
California Medical Research AssociatesNorthridgeCalifornia91324-
Diabetes Associates Medical GroupOrangeCalifornia92868-
University of California Irvine Medical CenterOrangeCalifornia92868-
FOMAT Medical ResearchOxnardCalifornia93030-
Desert Oasis Healthcare Medical GroupPalm SpringsCalifornia92262-
Dream Team Clinical ResearchPomonaCalifornia91767-
Rancho Cucamonga Clinical ResearchRancho CucamongaCalifornia91730-
Artemis Institute for Clinical ResearchRiversideCalifornia92503-
Acclaim Clinical ResearchSan DiegoCalifornia92120-
Artemis Institute for Clinical ResearchSan DiegoCalifornia92103-
Velocity Clinical Research, Santa AnaSanta AnaCalifornia92704-
Valiance Clinical ResearchTarzanaCalifornia91356-
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterTorranceCalifornia90502-
Diablo Clinical Research, Inc.Walnut CreekCalifornia94598-
Millennium Clinical TrialsWestlake VillageCalifornia91361-
University of Colorado Anschutz Medical CampusAuroraColorado80045-
Optum- SouthwesternColorado SpringsColorado80906-
Kidney Associates of ColoradoDenverColorado80210-
OptumCare Clinical Trials, LLCGoldenColorado80401-
Clinical Research ConsultingMilfordConnecticut06460-
Cardiology Associates of Fairfield County, P.C.StamfordConnecticut06905-
Chase Medical Research, LLCWaterburyConnecticut06708-
Excel Medical Clinical TrialsBoca RatonFlorida33434-
Encore Medical Research of Boynton BeachBoynton BeachFlorida33436-
Clinical Research of West Florida, Inc. (Clearwater)ClearwaterFlorida33765-
Northeast Research Institute (NERI)Fleming IslandFlorida32003-
Indago Research & Health Center, IncHialeahFlorida33012-
Northeast Research Institute - Downtown OfficeJacksonvilleFlorida32204-
IHS Health ResearchKissimmeeFlorida34741-
Clinical Research of Central FloridaLakelandFlorida33805-
South Florida Clinical Research InstituteMargateFlorida33063-
Felicidad Medical ResearchMiamiFlorida33184-
Floridian Clinical Research, LLCMiami LakesFlorida33016-1518-
Florida Institute For Clinical Research, LLCOrlandoFlorida32825-
Peace River Cardiovascular CenterPort CharlotteFlorida33952-
Northeast Research Institute - St. AugustineSaint AugustineFlorida32080-
IMA Clinical Research St. PetersburgSt. PetersburgFlorida33704-
Clinical Research of West FloridaTampaFlorida33606-
Metabolic Research Institute, Inc.West Palm BeachFlorida33401-
Masters of Clinical ResearchAugustaGeorgia30909-
HOPE Clinical Research & WellnessConyersGeorgia30094-
Center for Advanced Research & EducationGainesvilleGeorgia30501-
NSC ResearchJohns CreekGeorgia30024-
Balanced Life Health Care Solutions/SKYCRNGLawrencevilleGeorgia30046-
WR-Mount Vernon Clinical Research, LLCSandy SpringsGeorgia30328-
Rophe Adult and Pediatric Medicine/SKYCRNGUnion CityGeorgia30291-
North Georgia Clinical ResearchWoodstockGeorgia30189-
East-West Medical Research InstituteHonoluluHawaii96814-
Elite Clinical TrialsBlackfootIdaho83221-
Rocky Mountain Clinical ResearchIdaho FallsIdaho83404-
Solaris Clinical ResearchMeridianIdaho83646-
Velocity Clinical Research, BoiseMeridianIdaho83642-
IMA Clinical Research ChicagoChicagoIllinois60602-
Central Illinois Diabetes and Clinical Research a Division of Prairie Education and Research CooperativeSpringfieldIllinois62711-
Healthcare Research Network - ChicagoTinley ParkIllinois60477-
American Health Network of Indiana, LLC - AvonAvonIndiana46123-
Qualmedica Research, LLCEvansvilleIndiana47715-
American Health Network of Indiana, LLC - FranklinFranklinIndiana46131-
American Health Network of Indiana, LLC - GreenfieldGreenfieldIndiana46140-
Iowa Diabetes and Endocrinology Research CenterWest Des MoinesIowa50266-
Cotton O'Neil Diabetes & EndocrinologyTopekaKansas66606-
Cotton O'Neil MulvaneTopekaKansas66606-
Qualmedica ResearchBowling GreenKentucky42101-
L-MARC Research CenterLouisvilleKentucky40213-
Qualmedica Research, LLCOwensboroKentucky42301-
Ascension Saint Agnes Heart CareBaltimoreMaryland21229-
Centennial Medical GroupColumbiaMaryland21045-
Brigham and Women's Hospital Diabetes ProgramBostonMassachusetts02115-
Massachusetts General HospitalBostonMassachusetts02114-
NECCR PrimaCare ResearchFall RiverMassachusetts02721-
ActivMed Practices and ResearchMethuenMassachusetts01844-
Arcturus Healthcare , PLC, Troy Internal Medicine Research DivisionTroyMichigan48098-
M Health Fairview St. John's HospitalMaplewoodMinnesota55109-
The National Diabetes & Obesity Research InstituteDiamondheadMississippi39525-
Prime Health and Wellness/SKYCRNGFayetteMississippi39069-
Olive Branch Family Medical CenterOlive BranchMississippi38654-3514-
SKY Integrative Medical Center/SKYCRNGRidgelandMississippi39157-
StudyMetrix ResearchCity of Saint PetersMissouri63303-
Healthcare Research Network - St. LouisHazelwoodMissouri63042-
Clinvest Research LLCSpringfieldMissouri65807-
IMA Clinical Research - St. LouisSt LouisMissouri63117-
Billings ClinicBillingsMontana59101-
VA Nebraska-Western Iowa Health Care SystemOmahaNebraska68105-
DaVita Clinical Research - Las VegasLas VegasNevada89107-
Excel Clinical Research, LLCLas VegasNevada89109-
Palm Research Center SunsetLas VegasNevada89148-
Palm Research Center TenayaLas VegasNevada89128-
Advanced Research Institute - RenoRenoNevada89511-
UniMed CenterEast BrunswickNew Jersey08816-
NJ MedCare & NJ HeartLindenNew Jersey07036-
Hassman Research Institute Marlton SiteMarltonNew Jersey08053-
IMA Clinical Research WarrenWarren TownshipNew Jersey07059-
IMA Clinical ResearchAlbuquerqueNew Mexico87109-
Albany Medical College, Division of Community EndocrinologyAlbanyNew York12203-
Meridian Clinical Research, LLCBinghamtonNew York13905-
IMA Clinical ResearchNew YorkNew York10036-
NYU Langone HealthNew YorkNew York10016-
Rochester Clinical Research, LLCRochesterNew York14609-
Meridian Clinical Research, LLCVestalNew York13850-
Lillestol ResearchFargoNorth Dakota58104-
Aventiv Research IncColumbusOhio43213-
Alliance for Multispecialty Research, LLCNormanOklahoma73069-
The Corvallis Clinic, P.C.CorvallisOregon97330-
Heritage Valley Medical Group, Inc.BeaverPennsylvania15009-
Capital Area Research, LLCCamp HillPennsylvania17011-
Thomas Jefferson University HospitalPhiladelphiaPennsylvania19107-
Tristar Clinical InvestigationsPhiladelphiaPennsylvania19114-
Preferred Primary Care Physicians, Preferred Clinical Research-St. ClairPittsburghPennsylvania15243-
Cardiology Consultants of Philadelphia YardleyYardleyPennsylvania19067-
WR-Clinsearch, LLCChattanoogaTennessee37421-
Pinnacle Clinical ResearchAustinTexas78757-
Texas Diabetes & Endocrinology, P.A.AustinTexas78749-
Dallas Diabetes Research CenterDallasTexas75230-
Soma Clinical TrialsDenisonTexas75020-
Medresearch IncEl PasoTexas79902-
Diabetes and Thyroid Center of Ft. WorthFort WorthTexas76132-
Valley Institute of Research - Fort WorthFort WorthTexas76164-
AngioCardiac Care of Texas, PAHoustonTexas77025-
Biopharma Informatic, LLCHoustonTexas77043-
Biopharma Informatic, LLCHoustonTexas77084-
Houston Methodist HospitalHoustonTexas77030-
Next Level Urgent CareHoustonTexas77057-
Research Physicians Network, LLCHoustonTexas77089-
Epic Clinical ResearchLewisvilleTexas75057-
Texas Institute for Kidney and Endocrine DisordersLufkinTexas75904-
Biopharma Informatic, LLCMcAllenTexas78503-
Texas Institute of Cardiology, PAMcKinneyTexas75071-
Southern Endocrinology AssociatesMesquiteTexas75149-
North Hills Family Medicine/North Hills Medical ResearchNorth Richland HillsTexas76180-
Clinical Trials of Texas, LLCSan AntonioTexas78229-
Pinnacle Clinical ResearchSan AntonioTexas78229-
VIP TrialsSan AntonioTexas78230-
Consano Clinical Research, LLCShavano ParkTexas78231-
DaVita Clinical Research - North HoustonShenandoahTexas77384-
Northwest Houston Heart CenterTomballTexas77375-
Impact Research InstituteWacoTexas76710-
Texas Valley Clinical ResearchWeslacoTexas78596-
Soma Clinical TrialsWylieTexas75098-
Advanced Research InstituteOgdenUtah84405-
Advanced Research Institute - SandySandy CityUtah84070-
Kalo Clinical ResearchWest Valley CityUtah84120-
Dominion Medical Associates, Inc.RichmondVirginia23219-
National Clinical Research, IncRichmondVirginia23294-
Eastside Research AssociatesRedmondWashington98052-
Rainier Clinical Research CenterRentonWashington98057-
Central Washington Health Services Association d/b/a Confluence HealthWenatcheeWashington98801-
IMA Clinical ResearchMorgantownWest Virginia26505-
St. Vincent Hospital d/b/a Prevea HealthGreen BayWisconsin54303-

Find similar trials in Gilbert, AZ

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Prime Medical Group, LLC dba Gilbert Center for Family Medicine, LLC· Gilbert, AZAventiv Research· Mesa, AZElite Clinical Studies· Phoenix, AZPima Heart· Tucson, AZKLR Business Group, Inc. dba Arkansas Clinical Research· Little Rock, ARSmart Cures Clinical Research· Anaheim, CA

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