A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

Part of paid clinical trials in Northridge, California.

Sponsor
Eli Lilly and Company
Study ID
NCT05536804
Phase
PHASE2
Status
Active Not Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Tirzepatide — DRUG
    Administered SC
  • Placebo — DRUG
    Administered SC

Study Details

We are doing this study to learn more about how tirzepatide may help fight chronic kidney disease in people with obesity with or without type 2 diabetes (T2D). The study will last about 56 weeks and include up to 12 visits.

Key Dates

Start date
Feb 8, 2023
Status verified
May 2026
Primary completion
Sep 30, 2026
Completion
Oct 31, 2026

Study Design

Enrollment
140 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Tirzepatide
    Tirzepatide administered subcutaneously (SC)
  • Placebo Comparator: Placebo
    Placebo administered SC

Primary Outcome Measure

Percent Change from Baseline in Renal Sinus Fat Content (MRI) [ Time Frame: Baseline, Week 52 ]

Locations (10)

FacilityCityStateZIPSite coordinators
Valley Clinical Trials, Inc.NorthridgeCalifornia91325-
University of Colorado Anschutz Medical CampusAuroraColorado80045-
Kidney Associates of ColoradoDenverColorado80210-
American Health Network of Indiana, LLC - AvonAvonIndiana46123-
American Health Network of Indiana, LLC - GreenfieldGreenfieldIndiana46140-
Indiana University Health University HospitalIndianapolisIndiana46202-
American Health Network of Indiana, LLC - MuncieMuncieIndiana47304-
Arcturus Healthcare , PLC, Troy Internal Medicine Research DivisionTroyMichigan48098-
University of Washington Medical Center - MontlakeSeattleWashington98195-
Providence Medical Research Center - SpokaneSpokaneWashington99204-

Find similar trials in Northridge, CA

By condition
Chronic kidney diseaseObesity / overweightType 2 diabetes
By specialty
NephrologyKidney diseaseEndocrinologyMetabolic healthWeight loss
By research site
Valley Clinical Trials, Inc.· Northridge, CAUniversity of Colorado Anschutz Medical Campus· Aurora, COKidney Associates of Colorado· Denver, COAmerican Health Network of Indiana, LLC - Avon· Avon, INAmerican Health Network of Indiana, LLC - Greenfield· Greenfield, INIndiana University Health University Hospital· Indianapolis, IN

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