Establishing New Treatment Approaches for Amblyopia: Perceptual Learning and Video Games

Part of paid clinical trials in Fort Lauderdale, Florida.

Sponsor
Nova Southeastern University
Study ID
NCT05522972
Status
Recruiting
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Conditions

  • Amblyopia

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Accepted

Interventions

  • Video Game Vision Training — BEHAVIORAL
    A new approach for improving amblyopic vision using video games
  • Perceptual Learning — BEHAVIORAL
    A new approach for improving amblyopic vision with perceptual learning
  • Occlusion Therapy — BEHAVIORAL
    Conventional treatment for amblyopia

Study Details

Amblyopia, a developmental abnormality that impairs spatial vision, is a major cause of vision loss, resulting in reduced visual acuity and reduced sensitivity to contrast. This study uses psychophysical measures to study neural plasticity in both adults and children with amblyopia.

Key Dates

Start date
Sep 13, 2022
Status verified
Dec 2025
Primary completion
Aug 31, 2029
Completion
Aug 31, 2029

Study Design

Enrollment
180 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Experimental: Video Games
    Participants will be required to play video games for a period of time: 1-2 hrs per session, 4-5 sessions/week for \~1-6 months
  • Experimental: Perceptual learning
    Participants will be required to practice a visual discrimination task (e.g. visual acuity, position acuity, contrast sensitivity, \& stereoacuity) for a period of time: 1-2 hrs per session, 4-5 sessions/week for \~1-6 months
  • Active Comparator: Occlusion therapy
    Participants will be required to cover the dominant eye during the day in order to push the brain to use the fellow amblyopic eye: 1-2 hrs per session, 4-5 sessions/week for \~1-6 months

Primary Outcome Measure

Change in visual acuity before and after the intervention [ Time Frame: 9 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Nova Southeastern University College of OptometryFort LauderdaleFlorida33328
Roger Li, OD, PhD
[email protected]
954-262-1436

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By research site
Nova Southeastern University College of Optometry· Fort Lauderdale, FL

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