CARS: Cannabis and Alcohol Reduction Study
Part of paid clinical trials in Charleston, South Carolina.
- Sponsor
- Medical University of South Carolina
- Study ID
- NCT05486234
- Status
- Recruiting
Conditions
- Alcohol Use, Unspecified
- Cannabis Use
- Substance Use
- Substance Use Disorders
Eligibility Criteria
- Sex
- ALL
- Age
- 13 Years - 17 Years
- Healthy Volunteers
- Not accepted
Interventions
- modified Approach-Avoidance Task (mAAT), which aims to modify automatic approach bias — BEHAVIORALParticipants will undergo a baseline assessment before completing computerized tasks. During the baseline assessment, participants will be asked questions about alcohol and cannabis use. We will also ask questions about the way participants think about things, past life experiences related to substance use, and questions about how participants feel about reducing their substance use. Then, participants will complete a series computerized tasks where they will push and pull a joystick in response to images that are presented on a screen or where they will try to get a high score. During the computerized tasks, we will also be measuring brain activity using EEG. During the study, participants will also be asked to respond to questions about their health and behavior using an app on a smartphone or tablet using a secure program. Participants in the Treatment Group will then complete four sessions of the modified Approach-Avoidance Task (mAAT), which aims to modify automatic approach bias.
- modified Approach-Avoidance Task (mAAT) that does not aim to modify automatic approach bias. — BEHAVIORALParticipants will undergo a baseline assessment before completing computerized tasks. During the baseline assessment, participants will be asked questions about alcohol and cannabis use. We will also ask questions about the way participants think about things, past life experiences related to substance use, and questions about how participants feel about reducing their substance use. Then, participants will complete a series computerized tasks where they will push and pull a joystick in response to images that are presented on a screen or where they will try to get a high score. During the computerized tasks, we will also be measuring brain activity using EEG. During the study, participants will also be asked to respond to questions about their health and behavior using an app on a smartphone or tablet using a secure program. Participants in the Control Group will then complete four sessions of an Approach-Avoidance Task (mAAT) that does not aim to modify automatic approach bias.
Study Details
The study will test a computerized treatment with subjects ages 13-17 years who are seeking treatment for alcohol and/or cannabis use. Follow-up assessments will be conducted at one- and three-months following treatment.
Key Dates
- Start date
- Jan 25, 2023
- Status verified
- Mar 2026
- Primary completion
- Jul 31, 2026
- Completion
- Aug 1, 2026
Study Design
- Enrollment
- 52 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: Group A: Treatment Group
- Sham Comparator: Group B: Control Group
Primary Outcome Measure
Change in cannabis use as assessed by Timeline Followback [ Time Frame: Baseline and Three-Month Follow-up ]
Central Contacts
- Austin M Hahn, Ph.D.854-444-9456
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Medical University of South Carolina | Charleston | South Carolina | 29425 | Austin Hahn, Ph.D. 854-444-9456 |
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