Platelet Rich Plasma Testis Treatment for Infertile Men

Part of paid clinical trials in Stanford, California.

Sponsor
Stanford University
Study ID
NCT05479474
Status
Recruiting
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Conditions

  • Azoospermia
  • Male Infertility
  • Nonobstructive Azoospermia

Eligibility Criteria

Sex
MALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Platelet rich plasma — BIOLOGICAL
    Patients will undergo a blood draw (12 tsp) to prepare the PRP infusion. The use of a centrifuge and an Arteriocyte Magellan kit are necessary for the PRP preparation. After injection of local anesthesia, PRP will be injected into each testicle. * On the third month after the testicular PRP procedure, a TESE will be performed * If the procedure is successful a new IVF cycle using the sperm procured from the procedure will be done.

Study Details

Investigate the effect of intratesticular injection of autologous platelet rich plasma (PRP) on sperm retrieval rates and IVF outcomes in infertile men who already underwent a negative sperm retrieval. Currently, there is no alternative treatment after failed TESE. Prior series suggest that intratesticular PRP injections may improve TESE outcomes. We hope to determine whether PRP is an effective treatment for this patient population.

Key Dates

Start date
Jan 18, 2023
Status verified
Jan 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
10 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Platelet rich plasma treatment arm
    After consent in obtained, the patient will undergo a blood draw (12 tsp) to prepare the PRP infusion. The use of a centrifuge and an Arteriocyte Magellan kit are necessary for the PRP preparation. After injection of local anesthesia, PRP will be injected into each testicle.

Primary Outcome Measure

sperm present [ Time Frame: 3 months after PRP injection ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Stanford Urology ClinicStanfordCalifornia94304
Satvir Basran
[email protected]
650-723-0948

Find similar trials in Stanford, CA

By research site
Stanford Urology Clinic· Stanford, CA

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