Mental Health Crises in Youth With IDDs

Conditions

• Intellectual Disability

Eligibility Criteria

Sex

ALL

Age

7 Years - 17 Years

Healthy Volunteers

Not accepted

Interventions

• Genomic sequencing and molecular diagnostic results, if any. — GENETIC
  Genomic sequencing results may be used for diagnosis and treatment of participants.
• EHR-Based Network Model — OTHER
  EHR-based network will be created to predict psychiatric outcomes in youth with IDDs

Study Details

This study is an unmatched, case-control study of 150 youth (Ages 7-17) with a parent reported Intellectual Developmental Disability (IDD) who present to Rady Children's Hospital Emergency Department with a Mental Health Crisis (MHC). Rady Children's Institute for Genomic Medicine (RCIGM) will collect biological samples (such as blood) of these participants to study their genomes, medical and psychiatric profiles to better understand specific characteristics that may predispose them to MHC's. The 150 youth will be compared to historical, publicly available cohorts of youth with IDD's

Key Dates

Start date

Mar 29, 2023

Status verified

Aug 2024

Primary completion

Jul 1, 2026

Completion

Jul 1, 2027

Study Design

Enrollment

150 participants (estimated)

Arms

• Arm: Enrollees
  These participants will be subject to whole genome sequencing to identify genetic changes and a EHR-Based network model to predict psychiatric outcomes in youth with IDDs.
• Arm: Historical Control Group
  A historical control group from public databases will be used to compare against enrollees.

Primary Outcome Measure

Extract from Rady EHR demographic, biomedical, socioeconomic, and service use data for 150 youth with IDDs presenting to the ED for MHCs [ Time Frame: 4 years ]

Central Contacts

• Aaron Besterman, MD
  858-576-1700
  [email protected]
• Corrine Blucher, BS
  858-576-1700
  [email protected]

Locations (1)

Find similar trials in San Diego, CA

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