SV2A in Older Adults

Part of paid clinical trials in New Haven, Connecticut.

Sponsor
Yale University
Study ID
NCT05465538
Phase
PHASE1/PHASE2
Status
Recruiting
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Conditions

  • Cannabis Use

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • [11C]UCB-J PET — DRUG
    Single PET scan using the radioligand \[11C\]UCB-J

Study Details

The aim of the study is to examine the effect of cannabis use on brain synaptic density among older adults using \[11C\]UCB-J PET imaging.

Key Dates

Start date
Jul 6, 2022
Status verified
Feb 2026
Primary completion
Dec 30, 2026
Completion
Sep 30, 2027

Study Design

Enrollment
24 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Other: Cannabis using older adults
    Subjects undergo a single PET scan using \[11C\]UCB-J
  • Other: Healthy controls
    Subjects undergo a single PET scan using \[11C\]UCB-J

Primary Outcome Measure

Hippocampal synaptic density [ Time Frame: 1 month ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Conneticut Mental Health CenterNew HavenConnecticut06519
Angerlyk Frytz, MD
[email protected]
203-974-7822

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By research site
Conneticut Mental Health Center· New Haven, CT

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