Vascularized Composite Bladder Allograft Transplantation

Part of paid clinical trials in Los Angeles, California.

Sponsor
University of Southern California
Study ID
NCT05462561
Status
Recruiting
Apply to this trial

Conditions

  • Bladder Dysfunction
  • Immunosuppression
  • Neurogenic Bladder

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Quality-of-Life Assessment — OTHER
    Ancillary studies
  • Robotic Vascularized Composite Bladder Allograft Transplantation — PROCEDURE
    Undergo robotic VCBA transplantation.

Study Details

This phase 0 trial tests the feasibility, functionality, and sustainability of vascularized composite bladder allograft transplantation in treating patients with terminal bladder pathology. A vascularized bladder allograft transplantation may provide a more durable and better-tolerated alternative to standard urinary diversion, which employs bowel. A robotic surgical approach will be employed.

Key Dates

Start date
May 1, 2023
Status verified
Jan 2026
Primary completion
Oct 3, 2027
Completion
Oct 3, 2028

Study Design

Enrollment
5 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Treatment (VCBA)
    Patients undergo robotic VCBA transplantation.

Primary Outcome Measure

Technical success of vascularized composite bladder allograft (VCBA) transplantation [ Time Frame: At completion of transplantation procedure ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
USC / Norris Comprehensive Cancer CenterLos AngelesCalifornia90033
Ileana Aldana
[email protected]
323-865-3000
Inderbir Gill (PRINCIPAL_INVESTIGATOR)

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By research site
USC / Norris Comprehensive Cancer Center· Los Angeles, CA

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