Camrelizumab Plus Apatinib in Combination With GEMOX (Gemcitabine and Oxaliplatin ) in Patients With Locally Advanced Biliary Tract Cancer
- Sponsor
- First Affiliated Hospital of Zhejiang University
- Study ID
- NCT05451290
- Phase
- PHASE2
- Status
- Active Not Recruiting
Conditions
- Advanced Biliary Tract Carcinoma
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- Camrelizumab, apatinib, gemcitabine, oxaliplatin, tegafur — DRUGPerioperative treatment: camrelizumab plus apatinib in combination with GEMOX 2-4 cycles (neoadjuvant); camrelizumab plus S-1 up to 1 year (adjuvant).
Study Details
This is a phase II open-label, one-arm, multicenter study aimed to explore the efficacy and safety of perioperative (neoadjuvant and adjuvant) treatment for patients with advanced biliary tract carcinoma.
Key Dates
- Start date
- Nov 1, 2022
- Status verified
- Feb 2026
- Primary completion
- Dec 31, 2024
- Completion
- Dec 3, 2026
Study Design
- Enrollment
- 30 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: treatment arm
Primary Outcome Measure
1-year EFS rate [ Time Frame: 1 year ]
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