Transcranial Direct Current Stimulation (tDCS) in Human Subjects With PTSD Receiving an Exposure-based, Behavioral Therapy

Part of paid clinical trials in San Antonio, Texas.

Sponsor
The University of Texas Health Science Center at San Antonio
Study ID
NCT05419999
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Soterix 1x1 tDCS mini CT — DEVICE
    During stimulation, a current flows between the electrodes passing through the brain to complete the circuit. tDCS is hypothesized to modulate intrinsic neuronal activity by enhancing neuronal resting potential, or altering the likelihood that a neuron will (or will not) depolarize.
  • Sham Soterix 1x1 tDCS Mini CT — OTHER
    Sham setting is used on the Soterix transcranial electrical stimulator
  • Written Exposure Therapy (WET) — BEHAVIORAL
    An exposure-based, behavioral psychotherapy for PTSD.

Study Details

The primary objective of this study is to evaluate the safety, feasibility, and psychological and physiological treatment benefits of transcranial direct current stimulation (tDCS), a noninvasive brain stimulation technique, when delivered in combination with Written Exposure Therapy (WET), for posttraumatic stress disorder posttraumatic stress disorder (PTSD).

Key Dates

Start date
Jan 9, 2023
Status verified
May 2025
Primary completion
Apr 25, 2024
Completion
Apr 25, 2024

Study Design

Enrollment
25 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: tDCS plus WET
    Subjects will receive transcranial direct current stimulation (tDCS) plus written exposure therapy (WET)
  • Sham Comparator: Sham plus WET
    Subjects will receive sham transcranial direct current stimulation (tDCS) treatment plus written exposure therapy (WET)

Primary Outcome Measure

Posttraumatic Stress Disorder Checklist (PCL-5) [ Time Frame: Baseline to 9 weeks (one month post study treatment) ]

Locations (1)

FacilityCityStateZIPSite coordinators
The University of Texas Health Science Center at San AntonioSan AntonioTexas78229-

Find similar trials in San Antonio, TX

By condition
PTSD (post-traumatic stress disorder)
By specialty
PsychiatryMental healthBehavioral health
By research site
The University of Texas Health Science Center at San Antonio· San Antonio, TX

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