Autonomic Neuromodulation by Transcutaneous Nerve Stimulation in Acute Ischaemic Stroke.

Sponsor
Queen Mary University of London
Study ID
NCT05417009
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 95 Years
Healthy Volunteers
Not accepted

Interventions

  • trans-cutaneous auricular sensory stimulation — DEVICE
    Transcutaneous auricular sensory stimulation

Study Details

Autonomic modulation by transcutaneous vagal nerve stimulation in acute ischaemic stroke requiring mechanical thrombectomy: a phase IIa, sham controlled randomised trial.

Key Dates

Start date
Apr 26, 2023
Status verified
Jul 2025
Primary completion
Jul 21, 2023
Completion
Jul 21, 2023

Study Design

Enrollment
36 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Stimulation
    Electrodes attached bliaterally to tragus nerve region of outer ear, with appropriate device settings to deliver current.
  • Sham Comparator: Electrode attachment only.
    Electrodes attached bliaterally to tragus nerve region of outer ear, with device switched off \[blinded to operator\].

Primary Outcome Measure

Blood Pressure Variability [ Time Frame: 0-24h after mechanical thrombectomy ]

Related Studies