A Study to Learn How the Study Medicine Called PF-07275315 Works in Healthy People

Part of paid clinical trials in Lake Forest, California.

Sponsor
Pfizer
Study ID
NCT05411588
Phase
PHASE1
Status
Completed

Conditions

  • Healthy Volunteers

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

Study Details

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07275315) in healthy participants. This study is seeking participants who: * Are healthy as determined by medical evaluation. * Are willing and able to comply with all scheduled visits, treatment plan, laboratory tests, lifestyle considerations, and other study procedures. * Have a body mass index (BMI) of 17.5 to 32 kilogram per meter square - a total body weight of more than 50 kilograms (110 pounds) Participants will be divided randomly into 8 different groups. All participants will receive either one PF-07275315 or a harmless treatment that has no medical effect (placebo) intravenous (IV) infusion (given directly into a vein). Participants will take part in this study for up to 541 days. During this time, eligible participants will receive single increasing amounts of PF-07275315 or placebo. Increase will only occur if the sponsor agrees that the next dose is likely to have acceptable safety and tolerability. The follow-up visit will take place 271 days after first treatment.

Key Dates

Start date
Jun 9, 2022
Status verified
May 2025
Primary completion
May 13, 2024
Completion
May 13, 2024

Study Design

Enrollment
65 participants (actual)
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: Active
    PF-07275315
  • Placebo Comparator: Placebo
    Placebo

Primary Outcome Measure

Number of participants with Adverse Events (AEs) [ Time Frame: Baseline through study completion, approximately 561 days ]

Locations (4)

FacilityCityStateZIPSite coordinators
Orange County Research CenterLake ForestCalifornia92630-
Orange County Research CenterTustinCalifornia92780-
New Haven Clinical Research UnitNew HavenConnecticut06511-
Qps-Mra, LlcSouth MiamiFlorida33143-

Find similar trials in Lake Forest, CA

By research site
Orange County Research Center· Lake Forest, CAOrange County Research Center· Tustin, CANew Haven Clinical Research Unit· New Haven, CTQps-Mra, Llc· South Miami, FL

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